Fig. 4
From: β1 adrenoceptor antibodies induce myocardial apoptosis via inhibiting PGC-1α-related pathway
Overexpression of PGC-1α rescued β1AA induced apoptosis of H9C2 cells. a The expression of protein and mRNA of PGC-1α in the PGC-1α overexpression H9C2 cells. b Overexpression of PGC-1α rescued the inhibition of β1AA to cell proliferation in CCK8 assay. c Overexpression of PGC-1α decreased the apoptosis of the cells and inhibited the role of β1AA in promoting apoptosis in LDH assay. d TUNEL positive nuclei obtained from H9C2 cells visualized by fluorescence microscopy. Scale bar, 100 μm. e Group data of apoptosis rate of TUNEL assay. **, P ≤ 0.01. Group data presented by mean ± SEM