Skip to main content

Table 1 Clinical characteristics of study subjects

From: Early detection of left atrial and bi-ventricular myocardial strain abnormalities by MRI feature tracking in normotensive or hypertensive T2DM patients with preserved LV function

 

T2DM (n = 27)

T2DM-HT (n = 23)

Control (n = 31)

P value

Age (years)

54.1 ± 7.5

56.8 ± 6.5

54.1 ± 6.2

0.271

Male, n (%)

16(59.3)

12(52.2)

16(51.6)

0.819

BMI (kg/m2)

25.2 ± 3.4

26.1 ± 2.8$

24.2 ± 2.0

0.042

Diabetes duration (y)

8.0 ± 2.8

8.7 ± 3.1

–

0.673

Duration of hypertension (y)

–

4.8 ± 1.2

–

–

SBP (mmHg)

122.5 ± 7.9

131.7 ± 9.8$

123.9 ± 9.1

<0.001

DBP (mmHg)

73.9 ± 6.7

84.2 ± 8.6$

74.9 ± 8.0

<0.001

BUN (mmol/L)

5.2 ± 1.2

5.4 ± 1.9

–

0.059

creatinine (μmol/L)

69.0 ± 15.3

68.8 ± 14.2

–

0.527

Total cholesterol (mmol/L)

4.3 ± 0.9

4.5 ± 1.0

–

0.630

Triglycerides (mmol/L)

1.6 ± 1.5

1.6 ± 0.9

–

0.263

HDL-C (mmol/L)

1.3 ± 0.3

1.2 ± 0.3

–

0.986

LDL-C (mmol/L)

2.4 ± 0.7

2.7 ± 0.7

–

0.575

FPG (mmol/L)

8.1 ± 3.6

8.5 ± 2.9

–

0.596

Hemoglobin A1C (%)

9.4 ± 2.4

8.3 ± 2.2

–

0.639

Microalbuminuria (MA)

11.5 ± 6.3

9.0 ± 6.3

–

0.483

Diabetic complication, n (%)

 Retinopathy

7(25.9)

4(17.4)

–

0.353

 Neuropathy

5(18.5)

3(13)

–

0.448

 Peripheral vascular disease

4(14.8)

6(26.1)

–

0.261

Hypoglycemic medication, n (%)

 Insulin

13(48.1)

10(43.5)

–

0.482

 Metformin

16(59.3)

13(56.5)

–

0.569

 Sulphonylurea

4(14.8)

6(26.1)

–

0.261

Other medication, n (%)

 Statin

8(29.6)

6(26.1)

–

0.517

 Aspirin

7(25.9)

10(43.5)

–

0.157

Antihypertensive medication, n (%)

 ACEI

–

11(47.8)

–

–

 Diuretics

–

8 (34.7)

–

–

 Calcium channel blockers

–

3 (13.0)

–

–

 β-blockers

–

4 (17.4)

–

–

  1. All data expressed as mean ± SD, percentage (number of participants), or median (interquartile range), as appropriate. $ significant difference between T2DM-HT patients and control groups, p<0.05
  2. T2DM-HT, type 2 diabetes mellitus-hypertension; BMI, body mass index; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; BUN, blood urea nitrogen; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FPG, fasting plasma glucose; ACEI, angiotensin-converting enzyme inhibitor