Skip to main content

Table 2 High throughput multiplex analysis of biomarkers selected by supervised multivariate principal component analysis. Plasma concentrations of the assessed proteins are expressed on a log2-scale. Inter-group differences were assessed using analysis of variance method. *Bonferroni-corrected significant values (p < 0.0022)

From: Proteomic analysis reveals sex-specific biomarker signature in postural orthostatic tachycardia syndrome

BiomarkerPOTS+
(n = 113)
POTS-
(n = 283)
P-value*
TIM4.32 (0.08)4.49 (0.05)0.078
PSGL10.69 (0.04)0.8 (0.02)0.009
CTSL15.3 (0.04)5.46 (0.03)0.004
MB4.86 (0.07)5.14 (0.06)0.0020*
VEGFD6.7 (0.06)6.82 (0.03)0.062
PlGF7.1 (0.05)7.21 (0.04)0.131
MMP13.04 (0.14)3.41 (0.09)0.029
GDF158.22 (0.07)8.42 (0.05)0.058
FAS6.93 (0.04)7.02 (0.03)0.045
TF5.53 (0.04)5.61 (0.03)0.120
AM5.83 (0.09)6.05 (0.05)0.029
UPAR9.66 (0.03)9.72 (0.03)0.127
TNFR24.82 (0.04)4.9 (0.03)0.116
TRAIL8.44 (0.04)8.52 (0.03)0.183
MCP13.07 (0.05)3.24 (0.05)0.014
TRAILR21.21 (0.03)1.28 (0.02)0.080
OPG9.16 (0.04)9.25 (0.03)0.095
CASP81.45 (0.07)1.33 (0.05)0.126
HGF6.22 (0.04)6.34 (0.04)0.030
CD40L8.57 (0.11)8.6 (0.07)0.647
GH9.37 (0.26)8.37 (0.2)0.0019*
PTX31.38 (0.06)1.28 (0.04)0.124
SRC7.66 (0.07)7.77 (0.03)0.087