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Table 3 Pressure and arterial stiffness according to FBN1 genotype in males

From: Higher blood pressure in elderly hypertensive females, with increased arterial stiffness and blood pressure in females with the Fibrillin-1 2/3 genotype

 

2/2 genotype

2/3 genotype

2/4 genotype

 
 

n = 71

n = 14

n = 40

p-value

pMAP (mmHg)

102.4 ± 10.5

102.6 ± 15.5

100.3 ± 10.0

0.23

cSBP (mmHg)

139.6 ± 18

137.1 ± 23.3

138.3 ± 15.2

0.83

cDBP (mmHg)

78.2 ± 9.1

79.5 ± 13

77.1 ± 9.4

0.29

cPP (mmHg)

61.4 ± 16.7

57.6 ± 16.3

61.2 ± 12.8

0.67

cMAP (mmHg)

102.4 ± 10.5

102.6 ± 15.9

100.3 ± 9.9

0.60

AIx (%)

30.22 ± 9.47

34.11 ± 9.28

33.70 ± 7.71

0.052

AI hr75 (%)

25.8 ± 8.0

28.3 ± 6.6

26.8 ± 6.6

0.52

HR (beats/min)

66.0 ± 11.6

62.8 ± 10.8

60.5 ± 9.8

0.036

TR time (s)

132.9 ± 9.9

132.4 ± 8.7

131.9 ± 10.6

0.87

AG (mmHg)

19.5 ± 9.9

20.7 ± 10.2

21.2 ± 7.9

0.85

SBP right (mmHg)

164.7 ± 20.5

158.0 ± 23.1

159.8 ± 17.4

0.42

SBP left (mmHg)

159.1 ± 19.1

155.9 ± 18.6

157.6 ± 14.1

0.87

DBP right (mmHg)

80.9 ± 9.7

79.8 ± 8.37

79.4 ± 10.5

0.94

DBP left (mmHg)

79.8 ± 8.8

81.5 ± 11.8

79.7 ± 9.32

0.67

ABPI right (mmHg)

1.0 ± 0.3

1.1 ± 0.2

1.1 ± 0.2

0.64

ABPI left (mmHg)

1.0 ± 0.2

1.1 ± 0.2

1.0 ± 0.3

0.82

  1. All data are presented as the means ± SDs. pMAP Peripheral mean arterial pressure, cSBP Central systolic blood pressure, cDBP Central diastolic blood pressure, cPP Central pulse pressure, cMAP Central mean arterial pressure, AIx Augmentation index, AI hr75 Augmentation index heartrate 75, HR Heartrate, TR time Transistor time, AG Augmentation. Pressure: SBP Systolic blood pressure, DBP Diastolic blood pressure, ABPI Ankle brachial pressure index.