Table 2 Comparison of Demographic and Risk Factor Profiles in Participants with and Without Carotid Instability Plaque in the Derivation Set
From: A model to predict unstable carotid plaques in population with high risk of stroke
Variable | With Carotid Vulnerable Plaque (n = 174) | Without Carotid Vulnerable Plaque (n = 1720) | P Value | OR(95%CI) |
|---|---|---|---|---|
Sex (male) | 109 (62.6%) | 765 (44.5%) | <0.001 | 2.093 (1.518–2.887) |
Mean age (years) | ||||
40–49 | 14 (8.0%) | 207 (12.0%) | <0.001 | 1.00(Reference) |
50–59 | 35 (20.1%) | 512 (29.8%) | 0.018 | 5.686 (1.340–24.117) |
60–69 | 87 (50.0%) | 765 (44.5%) | <0.001 | 12.933 (3.160–52.934) |
≥ 70 | 38 (21.8%) | 236 (13.7%) | <0.001 | 27.500 (6.626–114.142) |
Education level (Primary school or below) | 67 (38.5%) | 663 (38.5%) | 0.992 | 0.998 (0.725–1.375) |
Marriage (married) | 141 (81.0%) | 1189 (69.1%) | 0.001 | 1.908 (1.289–2.826) |
Atrial fibrillation | 13 (7.5%) | 117 (6.8%) | 0.740 | 1.106 (0.610–2.007) |
Diabetes mellitus | 54 (31.0%) | 403 (23.4%) | 0.026 | 1.471 (1.047–2.066) |
Hypertension | 145 (83.3%) | 1358 (79.0%) | 0.175 | 1.333 (0.880–2.019) |
Hypercholesterolemia | 67 (38.5%) | 674 (39.2%) | 0.861 | 0.972 (0.705–1.339) |
Overweight or obesity | 61 (35.1%) | 786 (45.7%) | 0.008 | 0.641 (0.463–0.888) |
Smoking | 68 (39.1%) | 566 (32.9%) | 0.101 | 1.308 (0.949–1.802) |
Lack of Physical activity | 134 (77.0%) | 1309 (76.1%) | 0.789 | 1.052 (0.726–1.523) |
Family history of strok | 54 (31.0%) | 548 (31.9%) | 0.824 | 0.962 (0.687–1.348) |
FPG (mmol/L) | ||||
≤ 6.1 | 101 (58.0%) | 1192 (69.3%) | 0.007 | 1.0(Reference) |
6.11~6.99 | 29 (16.7%) | 235 (13.7%) | 0.091 | 1.456 (0.942–2.252) |
≥ 7.0 | 44 (25.3%) | 293 (17.0%) | 0.003 | 1.772 (1.216–2.582) |
HbA1c (> 6.5%) | 14 (8.0%) | 125 (7.3%) | 0.959 | 1.109 (0.496–2.094) |
Hcy(> 15 mmol/L) | 30 (17.2%) | 212 (12.3%) | 0.122 | 1.393 (0.915–2.120) |
TC(> 5.2 mmol/L) | 91 (52.3%) | 716 (41.6%) | 0.007 | 1.537 (1.125–2.101) |
LDL-C(> 3.12 mmol/L) | 97 (55.7%) | 704 (40.9%) | <0.001 | 1.467 (1.223–1.761) |
HDL-C (< 1.04 mmol/L) | 32 (18.4%) | 194 (11.3%) | 0.006 | 1.773 (1.175–2.675) |
TG(> 1.7 mmol/L) | 59 (33.9%) | 574 (33.4%) | 0.886 | 1.024 (0.737–1.424) |