Table 1 Baseline characteristics of the population included in the study
Indication for OAT | |||||||
|---|---|---|---|---|---|---|---|
Overall | Atrial fibrillation | MHV | VTE | Cardiopathy | Valvulopathies | Other | |
Patients N (%) | 927 (100) | 120 (12.9) | 465 (50.2) | 213 (23.0) | 36 (3.9) | 41 (4.4) | 52 (5.6) |
Age (median - IQR) | 58.1 [48–65.9] | 66.3 [58.7–70.9] | 60.8 [52.7–67.1] | 47.6 [38.4–56.6] | 52.7 [48.2–57.6] | 62.6 [57.5–68] | 48 [39.3–58.7] |
Female (%) | 431 (46.5) | 29 (24.2) | 234 (50.3) | 108 (50.7) | 8 (22.2) | 30 (73.2) | 22 (42.3) |
Time in traditional control of AVK, before PSM (years ± SD) | 8.5 ± 7.9 | 4.0 ± 4.1 | 11.4 ± 8.7 | 5.9 ± 6.1 | 6.4 ± 5.2 | 7.5 ± 6.1 | 5.0 ± 5.5 |
Previous major complications N (%) | |||||||
Thromboembolic | 113 (12.2) | 1 (0.8) | 86 (18.5) | 20 (9.4) | 0 (0) | 3 (7.3) | 3 (5.8) |
Hemorrhagic | 62 (6.7) | 5 (4.2) | 46 (9.9) | 4 (1.9) | 0 (0) | 1 (2.4) | 6 (11.5) |
Any | 163 (17.6) | 6 (5.0) | 121 (26.0) | 24 (11.3) | 0 (0) | 4 (9.8) | 8 (15.4) |
Comorbidities N (%) | |||||||
Any | 754 (81.3) | 110 (91.7) | 418 (89.9) | 115 (54.0) | 33 (91.7) | 39 (95.1) | 39 (75) |
> 3 | 202 (21.8) | 32 (26.7) | 129 (27.7) | 10 (4.7) | 12 (33.3) | 11 (26.8) | 8 (15.4) |
High blood pressure | 425 (45.9) | 81 (67.8) | 250 (53.8) | 48 (22.7) | 17 (47.1) | 17 (41.5) | 16 (31.7) |
Diabetes | 125 (13.4) | 23 (19.1) | 76 (16.3) | 10 (4.6) | 4 (10.5) | 10 (24.4) | 5 (10.0) |
Gastro duodenal ulcer | 50 (5.4) | 10 (8.0) | 31 (6.7) | 5 (2.5) | 2 (5.2) | 2 (4.9) | 1 (1.7) |
Cancer | 116 (12.5) | 24 (19.9) | 66 (14.2) | 11 (5.3) | 4 (10.5) | 4 (9.8) | 9 (16.7) |
Chronic liver disease | 30 (3.2) | 2 (1.6) | 23 (5.0) | 2 (0.7) | 1 (2.6) | 1 (2.4) | 2 (3.3) |
Ischemic heart disease | 93 (10.1) | 22 (18.3) | 50 (10.8) | 5 (2.5) | 8 (23.6) | 2 (4.9) | 7 (13.3) |
Heart failure | 126 (13.5) | 18 (15.1) | 86 (18.6) | 5 (2.5) | 12 (34.0) | 5 (12.2) | 3 (5.0) |
Peripheral vascular disease | 36 (3.9) | 11 (8.8) | 20 (4.4) | 1 (0.4) | 2 (5.2) | 0 (0.0) | 3 (6.7) |
Chronic renal insufficiency | 114 (12.3) | 18 (15.1) | 76 (16.3) | 6 (2.8) | 4 (10.5) | 8 (19.5) | 6 (11.7) |
Lipid disease | 405 (43.7) | 65 (54.2) | 237 (50.9) | 56 (26.3) | 14 (39.3) | 22 (53.7) | 14 (26.7) |
Atrial fibrillation | 279 (30.1) | 8 (6.4) | 222 (47.8) | 7 (3.2) | 18 (49.8) | 29 (70.7) | 7 (13.3) |
Chronic obstructive pulmonary disease | 74 (8.0) | 21 (17.5) | 35 (7.5) | 6 (2.8) | 6 (15.7) | 3 (7.3) | 4 (8.3) |
Others | 413 (44.6) | 56 (47.0) | 209 (45.1) | 86 (40.5) | 16 (44.5) | 18 (43.9) | 21 (40.0) |