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Table 1 Characteristics and unadjusted data of included studies

From: The important effect of 5-HTTLPR polymorphism on the risk of depression in patients with coronary heart disease: a meta-analysis

Reference

Country (Ethnicity)

Diagnosticcriteria for depression

Severity of depression

Sample size

CHD-D

CHD-nD

Genotype method

HWE

CHD-D

CHD-nD

S/S

L/S

L/L

S/S

L/S

L/L

Nakatani 2005 [11]

Japan (Asian)

SDS

Depression

861

942

552

281

28

592

298

52

PCR

Yes

Cao 2007 [12]

China (Asian)

CCMD-3; SDS; HAMD

Depression

153

171

95

46

12

96

67

8

PCR

Yes

Xia 2006 [17]

China (Asian)

CCMD-3; SDS

Depression

70

70

35

25

10

16

32

22

PCR

Yes

Otte 2007 [18]

America (White)

Interviews applying for DSM-IV criteria.

Depression

126

431

24

73

29

72

214

145

PCR

Yes

Kangelaris 2010 [19]

America (Mixed)

Interviews applying for DSM-IV criteria.

MDD

192

678

35

102

55

137

314

227

PCR

Yes

Kim 2015 [20]

Korea (Asian)

Interviews applying for DSM-IV criteria.

Depression

378

591

239

121

18

329

219

43

PCR

Yes

MDD

177

591

119

53

5

329

219

43

PCR

  1. CHD-D coronary heart disease comorbid depression, CHD-nD coronary heart disease without depression; Mixed,White, African American, Asian, Latino, Other; HWE Hardy-Weinberg equilibrium, PCR Polymerase Chain Reaction
  2. SDS The Zung Self-rating Depression Scale, HAMD Hamilton Depression Scale, DSM-IV Diagnostic and Statistical Manual of Mental Disorders, 4th Edition