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Table 4 Changes in the number of plaques and total plaque area between the baseline 4th survey (1994–95) and the 5th survey (2001) per 1 SD increase in baseline adiposity (number of plaques: n = 4345, total plaque area: n = 4302)

From: The association between anthropometric measures of adiposity and the progression of carotid atherosclerosis

Number of plaques

 

Model 1 β (95%CI)

p-value

Model 2 β (95%CI)

p-value

Model 3 β (95%CI)

p-value

BMI (per 1 SD)

−0.016 (−0.047, 0.015)

0.32

0.004 (− 0.028, 0.035)

0.82

− 0.011 (− 0.046, 0.023)

0.51

WC (per 1SD)

0.001 (− 0.030, 0.032)

0.97

0.014 (− 0.017, 0.045)

0.38

0.002 (− 0.031, 0.036)

0.89

WHR (per 1 SD)

0.029 (−0.002, 0.060)

0.07

0.032 (0.001, 0.064)

0.04

0.028 (−0.005, 0.061)

0.09

WHtR (per 1 SD)

0.010 (−0.021, 0.042)

0.52

0.024 (−0.008, 0.056)

0.14

0.013 (−0.021, 0.048)

0.45

Total plaque area

BMI (per 1 SD)

0.184 (−0.298, 0.666)

0.45

0.412 (−0.077, 0.902)

0.10

0.005 (−0.525, 0.534)

0.99

WC (per 1 SD)

0.468 (−0.014, 0.949)

0.06

0.608 (0.122, 1.094)

0.01

0.261 (−0.260, 0.782)

0.33

WHR (per 1 SD)

0.698 (0.211, 1.185)

0.005

0.697 (0.209, 1.186)

0.005

0.471 (−0.038, 0.980)

0.07

WHtR (per 1 SD)

0.614 (0.122, 1.106)

0.01

0.750 (0.252, 1.249)

0.003

0.397 (−0.138, 0.932)

0.15

  1. BMI body mass index, WC waist circumference, WHR waist-to-hip ratio, WHtR waist-to-height ratio, OR odds ratio, 95% CI 95% confidence interval, SD standard deviation, Model 1: adjusted for age and sex, Model 2: adjust for variables in Model 1 plus other confounders (smoking, physical activity and education), Model 3: adjusted for variables in Model 2 and mediators (systolic blood pressure, HDL cholesterol, non-HDL cholesterol, glycated haemoglobin, diabetes, lipid and blood pressure-lowering drug)