Table 1 Clinical characteristics of normotensive subjects and controlled hypertensive patients and those in hypertensive crisis (divided in hypertensive urgency and emergency)
From: Plasma levels of matrix metalloproteinase-9 are elevated in individuals with hypertensive crisis
Variable | NT (n = 40)a | CHyp (n = 58)b | HypUrg (n = 43)c | HypEmerg (n = 57)d | p-value (axbxcxd) | a x b | a x c | a x d | b x c | b x d | c x d |
|---|---|---|---|---|---|---|---|---|---|---|---|
Age (years) | 43.5 ± 10.2 | 57.7 ± 7.4 | 59.4 ± 15.6 | 62.4 ± 14.3 | <0.0001 | <0.01 | <0.01 | <0.01 | 0,09 | 0.10 | 0.09 |
Gender (male; %) | 11 (27.5) | 29 (50) | 21 (48.9) | 31 (54.4) | 0.03 | 0.16 | 0.01 | 0.20 | 0,24 | 0.16 | |
Skin color (White; %) | 33 (82.5) | 50 (86.2) | 27 (62.8) | 44 (77.2) | 0.12 | 0.10 | 0.12 | 0.009 | 0.11 | 0.12 | |
BMI (kg/m2) | 23.7 ± 3.3 | 29.6 ± 3.4 | 30.1 ± 7.2 | 27.6 ± 6.3 | 0.002 | <0.01 | <0.01 | 0.006 | 0.17 | 0.01 | 0.03 |
Smokers (%) | 6 (15%) | 11 (19) | 7 (16.3) | 17 (29.8) | 0.15 | 0.14 | 0.14 | 0.09 | 0.10 | 0.08 | |
History of diabetes (%) | – | 9 (15.5) | 12 (27.9) | 23 (40.3) | 0.009 | 0.0002 | 0.0001 | 0.14 | 0.003 | 0.09 | |
Blood Pressure | |||||||||||
SBP (mmHg) | 116.3 ± 11.8 | 123.2 ± 10.5 | 194.1 ± 28.6 | 191.6 ± 34.3 | <0.0001 | 0.16 | <0.01 | <0.01 | <0.01 | <0.01 | 0.10 |
DBP (mmHg) | 72.3 ± 9 | 79 ± 7.7 | 121.4 ± 17.3 | 121.7 ± 18.8 | <0.0001 | 0.14 | <0.01 | <0.01 | <0.01 | <0.01 | 0.09 |
Drugs, n(%) | |||||||||||
Antidiabetic drugs (%) | – | 16 (27.6) | 4 (9.3) | 13 (22.8) | – | – | – | 0.02 | 0.12 | 0.11 | |
Statins (%) | – | 14 (24.1) | 15 (34.9) | 22 (38.6) | – | – | – | 0.14 | 0.20 | 0.14 | |
Diuretics (%) | – | 48 (82.8) | 26 (60.4) | 29 (50.9) | – | – | – | 0.02 | 0.0003 | 0.12 | |
ARB (%) | – | 25 (43.1) | 16 (37.2) | 18 (28) | – | – | – | 0.09 | 0.14 | 0.17 | |
ACEi (%) | – | 22 (38) | 18 (41.8) | 31 (45.6) | – | – | – | 0.17 | 0.18 | 0.14 | |
CCB (%) | – | 18 (31) | 14 (32.6) | 18 (31.6) | – | – | – | 0.14 | 0.20 | 0.22 | |
B-blockers (%) | – | 16 (27.6) | 26 (60.4) | 27 (47.4) | – | – | – | 0.001 | 0.03 | 0.18 | |
Antiaggregant and/or anticoagulant (%) | – | 19 (32.8) | 19 (44.2) | 37 (64.9) | – | – | – | 0.20 | 0.0008 | 0.04 | |