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Table 3 Perioperative variables in age- and sex-matched patients

From: Heparin-binding protein measurement improves the prediction of myocardial injury-related cardiogenic shock

VariablesControl
(n = 620)
MIRCS
(n = 172)
P Value
HBP before aortic cross-clamping
 HBPCS1 (ng/ml)56.21 ± 33.5656.94 ± 26.370.79
 HBPCPB1 (ng/ml)40.65 ± 25.9542.53 ± 28.970.41
HBP after aortic declamping (5 min)
 HBPCS2 (ng/ml)163.13 ± 70.30266.58 ± 114.24< 0.01
 HBPCPB2 (ng/ml)151.97 ± 75.69193.52 ± 69.50< 0.01
Related variables
 HBPCS1 - HBPCPB1 (ng/ml)10.02(5.10, 22.01)7.01(0, 25.02)0.52
 HBPCS2 - HBPCPB2 (ng/ml)11.01(−2.00, 22.50)53.01(2.62, 84.75)< 0.01
 (HBPCS2 - HBPCS1) / HBPCS1 (%)2.15(1.37, 3.23)3.50(2.62, 5.39)< 0.01
 (HBPCPB2 - HBPCPB1) / HBPCPB1 (%)3.03(1.91, 4.78)4.36(2.18, 9.94)< 0.01
 HPB(CS-CPB) ratio (%)−0.14(−1.09, 1.22)0.95(−0.59, 7.54)< 0.01
 CI wean from CPB (L/min·m2)3.16 ± 0.441.85 ± 0.26< 0.01
 VIS wean from CPB25.42 ± 15.9751.02 ± 12.85< 0.01
 Lactate wean from CPB (mmol/L)2.10(1.40, 2.50)5.20 (5.10, 6.20)< 0.01
 cTnTCS2 (ug/L)1.19(0.98, 1.75)2.05(1.30, 2.76)< 0.01
Peripheral arterial cTnT (ug/L)
 5 min after aortic declamping0.52(0.19, 0.81)0.82 (0.51, 1.50)< 0.01
 At the end of surgery (T0)0.53(0.20, 0.83)0.93 (0.55, 1.29)< 0.01
 At the 3rd hour after surgery (T3)0.71(0.39, 0.96)0.98 (0.98, 1.30)< 0.01
 At the 24th hour after surgery (T24)0.68(0.56, 0.97)1.17 (0.91, 1.61)< 0.01
 At the 48th hour after surgery (T48)0.61 (0.47, 0.73)1.28 (1.11, 1.63)< 0.01
 At the 72nd hour after surgery (T72)0.51 (0.42, 0.75)1.11 (0.92, 1.37)< 0.01
Peripheral arterial HBP (ng/ml)
 At T0125.22 ± 28.17135.87 ± 32.67< 0.01
 At T3112.11 ± 31.25120.35 ± 25.350.03
 At T2491.17 ± 22.17119.82 ± 40.87< 0.01
 At T4884.04 ± 34.61116.06 ± 35.25< 0.01
  1. CI Cardiac Index, HBPCS Blood samples were obtained from coronary sinus, Time point 1 Before aortic cross-clamping, cTnT Cardiac troponin T, Median (Interquartile range), CPB Cardiopulmonary bypass, HBPCPB Blood samples were obtained from the arterial line of the CPB, Time point 2 5 min after aortic declamping, VIS Vasoactive-inotropic score, Mean ± SD, HPB(CS-CPB) ratio = [(HBPCS2 - HBPCPB2)- (HBPCS1 - HBPCPB1)] / (HBPCS1 - HBPCPB1)