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Table 3 Perioperative variables in age- and sex-matched patients

From: Heparin-binding protein measurement improves the prediction of myocardial injury-related cardiogenic shock

Variables

Control

(n = 620)

MIRCS

(n = 172)

P Value

HBP before aortic cross-clamping

 HBPCS1 (ng/ml)

56.21 ± 33.56

56.94 ± 26.37

0.79

 HBPCPB1 (ng/ml)

40.65 ± 25.95

42.53 ± 28.97

0.41

HBP after aortic declamping (5 min)

 HBPCS2 (ng/ml)

163.13 ± 70.30

266.58 ± 114.24

< 0.01

 HBPCPB2 (ng/ml)

151.97 ± 75.69

193.52 ± 69.50

< 0.01

Related variables

 HBPCS1 - HBPCPB1 (ng/ml)

10.02(5.10, 22.01)

7.01(0, 25.02)

0.52

 HBPCS2 - HBPCPB2 (ng/ml)

11.01(−2.00, 22.50)

53.01(2.62, 84.75)

< 0.01

 (HBPCS2 - HBPCS1) / HBPCS1 (%)

2.15(1.37, 3.23)

3.50(2.62, 5.39)

< 0.01

 (HBPCPB2 - HBPCPB1) / HBPCPB1 (%)

3.03(1.91, 4.78)

4.36(2.18, 9.94)

< 0.01

 HPB(CS-CPB) ratio (%)

−0.14(−1.09, 1.22)

0.95(−0.59, 7.54)

< 0.01

 CI wean from CPB (L/min·m2)

3.16 ± 0.44

1.85 ± 0.26

< 0.01

 VIS wean from CPB

25.42 ± 15.97

51.02 ± 12.85

< 0.01

 Lactate wean from CPB (mmol/L)

2.10(1.40, 2.50)

5.20 (5.10, 6.20)

< 0.01

 cTnTCS2 (ug/L)

1.19(0.98, 1.75)

2.05(1.30, 2.76)

< 0.01

Peripheral arterial cTnT (ug/L)

 5 min after aortic declamping

0.52(0.19, 0.81)

0.82 (0.51, 1.50)

< 0.01

 At the end of surgery (T0)

0.53(0.20, 0.83)

0.93 (0.55, 1.29)

< 0.01

 At the 3rd hour after surgery (T3)

0.71(0.39, 0.96)

0.98 (0.98, 1.30)

< 0.01

 At the 24th hour after surgery (T24)

0.68(0.56, 0.97)

1.17 (0.91, 1.61)

< 0.01

 At the 48th hour after surgery (T48)

0.61 (0.47, 0.73)

1.28 (1.11, 1.63)

< 0.01

 At the 72nd hour after surgery (T72)

0.51 (0.42, 0.75)

1.11 (0.92, 1.37)

< 0.01

Peripheral arterial HBP (ng/ml)

 At T0

125.22 ± 28.17

135.87 ± 32.67

< 0.01

 At T3

112.11 ± 31.25

120.35 ± 25.35

0.03

 At T24

91.17 ± 22.17

119.82 ± 40.87

< 0.01

 At T48

84.04 ± 34.61

116.06 ± 35.25

< 0.01

  1. CI Cardiac Index, HBPCS Blood samples were obtained from coronary sinus, Time point 1 Before aortic cross-clamping, cTnT Cardiac troponin T, Median (Interquartile range), CPB Cardiopulmonary bypass, HBPCPB Blood samples were obtained from the arterial line of the CPB, Time point 2 5 min after aortic declamping, VIS Vasoactive-inotropic score, Mean ± SD, HPB(CS-CPB) ratio = [(HBPCS2 - HBPCPB2)- (HBPCS1 - HBPCPB1)] / (HBPCS1 - HBPCPB1)