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Table 2 Univariate and multiple logistic regression analysis displaying independent predictors for isolated coronary artery ectasia

From: Neutrophil activation and neutrophil derived neutrophil extracellular trap formation in patients with coronary artery ectasia

 

CAE

non-CAE

Univariate regression

Multiple regression

p value

OR (95%CI)

p value

OR (95%CI)

Number of patients

30

60

    

Age (year)

57.37 ± 13.82

58.42 ± 10.68

0.688

0.99(0.96–1.03)

  

Sex (Female, %)

20

25

0.598

0.75(0.26–2.18)

  

Hypertension (%)

60

58.3

0.880

1.07(0.44–2.62)

  

DM (%)

16.7

21.7

0.577

0.72(0.23–2.26)

  

Smokers (%)

46.7

46.7

1.000

1(0.42–2.41)

  

Alcohol consumption (%)

16.7

21.7

0.577

0.72(0.23–2.26)

  

Family history of CAD (%)

6.7

11.7

0.462

0.54(0.11–2.78)

  

Systolic Blood Pressure (mmHg)

132.27 ± 18.52

129.30 ± 18.10

0.465

1.01(0.99–1.03)

  

Diastolic Blood Pressure (mmHg)

78.73 ± 13.48

73.22 ± 11.96

0.058

1.04(1–1.07)

0.387

1.02(0.98–1.07)

Heart rate (bpm)

72.90 ± 12.10

70.28 ± 9.76

0.271

1.02(0.98–1.07)

  

BMI (kg/m2)

26.99 ± 3.96

25.57 ± 2.72

0.052

1.15(1.00–1.32)

0.058

1.17(1–1.36)

ALT (U/L)

31.03 ± 18.79

28.33 ± 15.74

0.471

1.01(0.98–1.04)

  

Creatinine (μmol/L)

134.9 ± 230.11

78.62 ± 14.78

0.337

1.01(0.99–1.02)

  

LDL-C (mmol/L)

2.34 ± 0.71

2.32 ± 0.67

0.888

1.05(0.55–2)

  

WBC (109cell/L)

6.89 ± 2.25

6.76 ± 1.75

0.754

1.04(0.83–1.3)

  

Neut# (109cell/L)

5.49 ± 2.57

5.07 ± 6.63

0.738

1.01(0.94–1.09)

  

HGB (g/L)

141.07 ± 21.56

142.07 ± 16.26

0.804

1(0.97–1.02)

  

PLT (109cell/L)

211.57 ± 65.15

214.15 ± 59.14

0.849

1(0.99–1.01)

  

MPXI

1.02 ± 3.01

3.37 ± 3.67

0.005*

0.81(0.70–0.94)

0.029*

0.84(0.71–0.98)

dsDNA, ng/mL

284.31(258.33–449.91)

240.16(213.43–270.02)

0.004*

1.01 (1.00–1.01)

0.006*

1.01(1.00–1.01)

  1. CAE Coronary artery ectasia, CAD Coronary artery disease, DM Diabetes mellitus, BMI Body mass index, ALT Alanine aminotransferase, LDL-C low-density lipoprotein-cholesterol, MPO Myeloperoxidase, MPXI Intra-neutrophil mean MPO index, WBC# White blood cell, Neut# Neutrophil leucocyte count, HGB Hemoglobin, PLT Platelet count
  2. *Statistically significant