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Table 1 Baseline characteristics of the patients

From: Novel myocardial markers GADD45G and NDUFS5 identified by RNA-sequencing predicts left ventricular reverse remodeling in advanced non-ischemic heart failure: a retrospective cohort study

variables

RR group

(n = 8)

non-RR group

(n = 9)

P value

Age

46.1 ± 14.3

47.1 ± 9.4

0.87

Male Sex, n

6

8

0.45

Disease duration (months)

36.1 ± 65.5

79.0 ± 46.5

0.14

Height (cm)

165 ± 9

168 ± 5

0.35

Weight (kg)

64.1 ± 12.5

67.2 ± 9.4

0.56

BMI

23.4 ± 3.9

23.8 ± 3.2

0.83

HR (bpm)

90 ± 23

84 ± 20

0.63

Method of biopsy (transcatheter /surgery)

4/4

0/9

0.019

Treatment

 Beta-blocker, n

7

8

0.93

 ACEI or ARB, n

6

8

0.45

 Inotropes, n

2

8

0.008

 IABP, n

0

2

0.16

 AVR, n

2

1

0.45

 VAD implantation, n

2

8

0.008

Labo data

 Hb (g/dL)

12.8 ± 2.3

11.4 ± 1.7

0.17

 T-Bil (mg/dl)

1.1 ± 0.3

1.2 ± 0.8

0.70

 Cre (mg/dl)

0.92 ± 0.36

1.40 ± 0.45

0.029

 BNP (pg/ml)

725 ± 454

475 ± 177

0.15

Echocardiogram

 LVDD (mm)

72 ± 10

79 ± 12

0.19

 LVDS (mm)

65 ± 8

72 ± 12

0.20

 LVEF (%)

21.5 ± 5.1

20.4 ± 4.2

0.63

 LAD (mm)

50 ± 9

54 ± 11

0.43

 AR (moderate to severe, n)

2

1

0.45

 MR (moderate to severe, n)

6

6

0.71

 TR (moderate to severe, n)

2

3

0.71

Hemodynamics

 PAP, mean (mmHg)

36 ± 10

38 ± 10

0.60

 PCWP, mean (mmHg)

27 ± 6

29 ± 9

0.57

 RAP, mean (mmHg)

10 ± 2

13 ± 6

0.16

 CO (L/min)

4.02 ± 0.68

3.79 ± 0.90

0.56

 CI (L/min/m2)

2.30 ± 0.34

2.06 ± 0.47

0.25

 PVR (Wood)

2.41 ± 1.66

2.45 ± 1.61

0.96

  1. Data are shown as the mean value ± standard deviation, or number of the patients
  2. Abbreviations: BMI body mass index; HR heart rate; ACEI angiotensin converting enzyme inhibitor; ARB angiotensin II receptor blocker; IABP intraaortic balloon pumping; AVR aortic valve replacement; VAD ventricular assist device; Hb hemoglobin; T-Bil total bilirubin; Cre creatinine; LVDD left ventricular diastolic diameter; LVDS left ventricular systolic diameter; LVEF left ventricular ejection fraction; LAD left atrial diameter; AR aortic regurgitation; MR mitral regurgitation; TR tricuspid regurgitation; PAP pulmonary artery pressure; PCWP pulmonary capillary wedge pressure; RAP right atrial pressure; CO cardiac output; CI cardiac index; PVR pulmonary vascular resistance