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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Inhibition of JAK2/STAT3/SOCS3 signaling attenuates atherosclerosis in rabbit

Fig. 2

Ruxolitinib decreased the lipid burden and calcium burden in plaques of atherosclerotic rabbits. (a) Oil Red O staining for the deposition of lipid droplets. Dark-staining red drops: positive areas of Oil Red O staining; quantification determined by WinROOF ver.6 (right). **P < 0.01 versus control group; ##P < 0.01 versus model group. Data were analyzed by using Student’s t-test and expressed as mean ± SD (n = 3). (b) Alizarin Red S staining for calcium burden in plaques. The emergence of mineralized nodules (Dark-staining red areas, marked by the black arrow) was considered as positive

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