Table 2 Medication Use in Intervals 1 (6 months after diagnosis) and 3 (1–1.5 years after diagnosis)

Characteristics

Overall

1st Pulse Rate Decile

5th Pulse Rate Decile

10th Pulse Rate Decile

p-value

Overall

1st Pulse Rate Decile

5th Pulse Rate Decile

10th Pulse Rate Decile

p-value

N = 44,093

(47–59 bpm)

(72–75 bpm)

(97–117 bpm)

N = 44,093

(47–59 bpm)

(72–75 bpm)

(97–117 bpm)

n = 6116

n = 4753

n = 2269

n = 6433

n = 5094

n = 2214

ACE Inhibitor or ARB, %

31,716 (77.2%)

4808 (78.6%)

3626 (76.3%)

1741 (76.7%)

0.0007

28,970 (67.0%)

4523 (70.3%)

3433 (67.4%)

1349 (60.9%)

<.0001

Aldosterone Antagonists, %

6574 (16.0%)

878 (14.4%)

789 (16.6%)

410 (18.1%)

<.0001

6374 (14.8%)

838 (13.0%)

778 (15.3%)

308 (13.9%)

<.0001

Beta blocker, %

33,407 (81.3%)

5177 (84.6%)

3861 (81.20%)

1696 (74.7%)

<.0001

31,735 (73.4%)

5031 (78.2%)

3804 (74.7%)

1373 (62.0%)

<.0001

Calcium channel blocker, %

8626 (21.0%)

1536 (25.1%)

945 (19.9%)

404 (17.8%)

<.0001

7861 (18.2%)

1442 (22.4%)

890 (17.5%)

353 (15.9%)

<.0001

Statins, %

29,996 (73.00%)

4644 (75.9%)

3488 (723.4%)

1480 (65.2%)

<.0001

28,950 (67.0%)

4579 (71.2%)

3401 (66.8%)

1253 (56.6%)

<.0001

Nitrates, %

8435 (20.5%)

1426 (23.3%)

1935 (19.7%)

397 (17.5%)

<.0001

7164 (16.6%)

1221 (19.0%)

830 (16.3%)

274 (12.4%)

<.0001

Loop Diuretic, %

20,508 (49.9%)

2847 (48.25%)

2394 (50.4%)

1287 (56.7%)

<.0001

18,575 (43.0%)

2642 (41.1%)

2243 (44.0%)

962 (43.5%)

0.0084

Thiazides, %

5838 (14.2%)

939 (15.4%)

666 (14.0%)

323 (14.2%)

0.1137

4670 (10.8%)

785 (12.2%)

540 (10.6%)

2055 (9.3%)

0.005

Anticoagulant, %

4017 (9.8%)

639 (10.4%)

456 (9.6%)

241 (10.6%)

0.1794

3715 (8.6%)

644 (10.0%)

407 (8.0%)

189 (8.5%)

<.0001

Digoxin, %

4410 (10.7%)

598 (9.8%)

518 (10.9%)

287 (12.6%)

0.0105

4176 (9.7%)

507 (7.9%)

511 (10.0%)

234 (10.6%)

<.0001