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Fig. 1 | BMC Cardiovascular Disorders

Fig. 1

From: Up-regulating autophagy by targeting the mTOR-4EBP1 pathway: a possible mechanism for improving cardiac function in mice with experimental dilated cardiomyopathy

Fig. 1

Modulating autophagy and cardiac matrix remodeling of DCM. (A) Picrosirius red staining indicated significantly changes of collagen distribution in the four different groups. (B) Histochemical analysis showed that there was a significant increase of collagen distribution in the DCM group compared with the control group. Quantitative assessment demonstrated that the CVF was significantly decreased in the rapamycin group, and it was increased in the 3-MA group compared with the DCM group. †††P < 0.001 vs Control, **P < 0.01 and #P < 0.05 vs DCM. Scale bar = 100 μm

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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