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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Activating the interleukin-6-Gp130-STAT3 pathway ameliorates ventricular electrical stability in myocardial infarction rats by modulating neurotransmitters in the paraventricular nucleus

Fig. 2

Effects of PVN infusion of an anti-IL-6 antibody or SC144 on IL-6, Gp130 and pSTAT3 levels within the MI rats. a Representative image of IL-6 immunohistochemical staining. b Densitometric analysis of IL-6 staining. c Representative image of Gp130 immunohistochemical staining. d Densitometric analysis of Gp130 staining. e Representative image of pSTAT3 immunohistochemical staining. f Densitometric analysis of pSTAT3 staining. g Representative immunoblot image of IL-6, Gp130 and pSTAT3 levels. h-j Densitometric analysis of the protein expression of IL-6, Gp130 and pSTAT3 (n = 4). The values are the means ± SEs. &p < 0.05 vs sham rats, #p < 0.05 vs MI rats. Abbreviations: PVN, paraventricular nucleus; IL-6, interleukin-6; MI, myocardial infarction; Gp130, glycoprotein 130

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