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Table 2 Changes in parameters related to CKD-MBD and atherosclerosis

From: Comparison of the effects of lanthanum carbonate and calcium carbonate on the progression of cardiac valvular calcification after initiation of hemodialysis

 

LC (n = 24)

CC (n = 26)

0 M

18 M

0 M

18 M

cCa (mg/dL)

8.5 ± 0.8

8.8 ± 0.8

8.4 ± 0.8

9.2 ± 0.6†

P (mg/dL)

6.0 ± 1.3

5.5 ± 1.2

5.9 ± 1.5

5.1 ± 1.4

iPTH (pg/mL)

216.0 (128.5–531.8)

155.0 (69.1–194.5)*

281.0 (217.8–422.5)

98.5 (38.0–192.8)†

iFGF23 (pg/mL)

737.5 (456.8–1875.9)

2430.5 (750.8–7560.8)*

588.1 (264.5–1880.6)

2630.4 (747.1–13,741.8)†

LDL-C (mg/dL)

86.0 ± 37.2

84.4 ± 24.4

86.8 ± 30.6

73.6 ± 23.1†

PS

6.7 (3.8–14.1)

9.2 (4.8–18.0)*

5.6 (1.3–11.6)

7.0 (3.3–12.8)†

  1. Values are presented as the median and interquartile or mean ± SD
  2. LC lanthanum carbonate group, CC calcium carbonate, cCa corrected calcium, P phosphorus, iPTH intact parathyroid hormone, iFGF23 intact fibroblast growth factor 23, LDL-C low density lipoprotein cholesterol, PS plaque score
  3. *LC at 0 M versus LC at 18 M, p < 0.05; †CC at 0 M versus CC at 18 M, p < 0.05