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Table 6 Comparison between participants with ΔFMD < 10% and those with ΔFMD ≥10%

From: Influencing factors of vascular endothelial function in patients with non-obstructive coronary atherosclerosis: a 1-year observational study

 ΔFMD < 10% (n = 55)ΔFMD ≥10% (n = 71)P-value
Baseline FMD, %9.92 ± 5.486.11 ± 4.51< 0.001
1-year FMD, %9.35 ± 5.719.28 ± 5.610.951
Age, years58.62 ± 10.7460.51 ± 11.190.387
Male, n (%)27 (49.1)35 (49.3)0.944
Body mass index, kg/m225.60 ± 3.6925.50 ± 3.370.891
Smoking, n (%)14 (25.5)14 (19.7)0.803
Diabetes mellitus, n (%)19 (34.5)11 (15.5)0.017
Family history of premature cardiovascular diseases, n (%)14 (25.5)13 (18.3)0.644
Hypertension, n (%)23 (41.8)45 (63.4)0.012
Heart rate, beats/min71.66 ± 10.4071.58 ± 10.120.970
Systolic blood pressure, mmHg129.14 ± 16.95137.46 ± 14.660.010
Diastolic blood pressure, mmHg75.09 ± 8.6674.64 ± 10.870.733
Pulse pressure, mmHg54.05 ± 14.6063.04 ± 16.040.005
Serum creatinine, μmol/L69.02 ± 14.4163.55 ± 16.070.081
Uric acid, mmol/L330.23 ± 80.96321.93 ± 100.050.657
Glucose, mmol/L5.41 ± 1.635.52 ± 1.210.715
HbA1c, %6.06 ± 1.076.21 ± 0.700.468
Total cholesterol, mmol/L1.72 ± 0.691.68 ± 0.840.795
Triglyceride, mmol/L4.24 ± 0.884.21 ± 0.890.884
High-density lipoprotein cholesterol, mmol/L1.27 ± 0.311.38 ± 0.370.116
Low-density lipoprotein cholesterol, mmol/L2.50 ± 0.742.39 ± 0.650.448
Homocysteine, μmol/L12.28 ± 2.8914.53 ± 5.690.132
Ejection fraction, %64.26 ± 6.5265.95 ± 7.240.291
MedicationsΔFMD < 10% (n = 55)ΔFMD ≥10% (n = 71)P-value
Antiplatelet therapy37 (67.2)48 (67.6)0.879
ACE-I/ARB21 (38.2)35 (49.3)0.193
β-blockers27 (49.1)41 (57.7)0.291
Calcium channel blockers11 (20.0)17 (23.9)0.549
Diuretics4 (7.3)6 (8.5)0.777
Statins37 (67.3)49 (69.0)0.462
Hypoglycemic agents18 (32.7)11 (15.5)0.017
White blood cell, ×109/L6.35 ± 1.426.87 ± 1.940.542
Neutrophil, ×109/L3.53 ± 1.373.83 ± 1.700.352
Lymphocytes, ×109/L2.23 ± 0.902.02 ± 0.620.169
Neutrophil-to-lymphocyte ratio1.92 ± 1.352.00 ± 0.920.736
Red blood cell distribution width, %12.76 ± 0.6312.96 ± 0.870.191
High-sensitivity C-reactive protein, mg/L5.65 ± 11.425.95 ± 11.740.944
Endothelial progenitor cells per 106 cells36.11 ± 15.1659.14 ± 24.36< 0.001
  1. FMD flow-mediated dilatation; ACE-I/ARB, ACE-I/ARB angiotensin-converting-enzyme inhibitors / angiotensin II receptor blockers