| FMD < 6% (n = 65) | FMD ≥ 6% (n = 66) | P-value |
---|---|---|---|
FMD, % | 3.11 ± 1.69 | 11.45 ± 4.17 | < 0.001 |
Age, year | 60.74 ± 11.41 | 59.56 ± 10.99 | 0.548 |
Male, n (%) | 30 (46.2) | 32 (48.5) | 0.771 |
Body mass index, kg/m2 | 25.82 ± 3.86 | 25.46 ± 3.16 | 0.584 |
Smoking, n (%) | 13 (20.3) | 15 (23.1) | 0.689 |
Diabetes mellitus, n (%) | 19 (29.7) | 11 (16.9) | 0.121 |
Family history of premature cardiovascular disease, n (%) | 13 (20.0) | 14 (21.2) | 0.839 |
Hypertension, n (%) | 33 (50.8) | 35 (53.0) | 0.778 |
Statins, n (%) | 10 (15.4) | 18 (27.3) | 0.106 |
β-blocker, n (%) | 16 (24.6) | 12 (18.8) | 0.419 |
Calcium channel blockers, n (%) | 16 (24.6) | 19 (28.8) | 0.589 |
Angiotensin-converting enzyme inhibitors / angiotensin II receptor blockers, n (%) | 19 (29.2) | 16 (24.2) | 0.519 |
Heart rate, beats/min | 70.98 ± 11.42 | 72.73 ± 9.52 | 0.351 |
Systolic blood pressure, mmHg | 138.38 ± 16.41 | 130.69 ± 16.25 | 0.008 |
Diastolic blood pressure, mmHg | 74.75 ± 10.72 | 75.88 ± 10.43 | 0.546 |
Pulse pressure, mmHg | 63.75 ± 16.29 | 54.89 ± 14.75 | 0.001 |
Serum creatinine, μmol/L | 65.64 ± 17.08 | 67.53 ± 14.02 | 0.497 |
Uric acid, mmol/L | 338.73 ± 109.08 | 329.95 ± 75.89 | 0.600 |
Glucose, mmol/L | 5.68 ± 1.60 | 5.40 ± 1.37 | 0.290 |
HbA1c, % | 6.49 ± 0.94 | 5.79 ± 0.53 | < 0.001 |
Total cholesterol, mmol/L | 1.79 ± 1.19 | 1.75 ± 0.78 | 0.822 |
Triglyceride, mmol/L | 4.04 ± 0.76 | 4.33 ± 0.89 | 0.058 |
High-density lipoprotein cholesterol, mmol/L | 1.30 ± 0.36 | 1.35 ± 0.32 | 0.493 |
Low-density lipoprotein cholesterol, mmol/L | 2.26 ± 0.62 | 2.51 ± 0.70 | 0.035 |
Homocysteine, μmol/L | 15.11 ± 12.04 | 13.22 ± 3.92 | 0.439 |
Ejection fraction, % | 66.90 ± 6.58 | 64.46 ± 7.52 | 0.093 |
White blood cell, ×109/L | 6.27 ± 1.71 | 6.87 ± 1.94 | 0.068 |
Neutrophil, ×109/L | 3.55 ± 1.49 | 3.97 ± 1.68 | 0.140 |
Neutrophil-to-lymphocyte ratio | 2.08 ± 1.25 | 1.97 ± 1.12 | 0.618 |
Red blood cell distribution width, % | 12.73 ± 2.76 | 12.93 ± 0.73 | 0.818 |
High-sensitivity C-reactive protein, mg/L | 3.37 ± 4.13 | 7.87 ± 14.31 | 0.160 |
Endothelial progenitor cells per 106 cells | 52.00 ± 22.13 | 46.59 ± 24.78 | 0.254 |