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Table 4 Hazard Ratios (95% Confidence Intervals) of Atrial Fibrillation by Categories of Blood Pressure According to JNC 7 and 2017 ACC/AHA Definitions, ARIC 1987–2015

From: Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study

JNC 7NormalPrehypertensionHypertension
No. of AF cases9417241226
No. of participants624936195047
Person-years142,74277,84998,426
Incidence rate (per 1000 PY)6.69.312.5
Model 1 [HR (95%CI)]1 (ref.)1.30 (1.17, 1.43)1.90 (1.73, 2.07)
Model 2 [HR (95%CI)]1 (ref.)1.24 (1.12, 1.36)1.58 (1.44, 1.74)
2017 ACC/AHANormalElevatedStage 1Stage 2
No. of AF cases9413423821226
No. of participants6249156220575047
Person-years142,74233,18344,66698,426
Incidence rate (per 1000 PY)6.610.38.612.5
Model 1 [HR (95%CI)]1 (ref.)1.36 (1.20, 1.54)1.24 (1.10, 1.40)1.90 (1.73, 2.07)
Model 2 [HR (95%CI)]1 (ref.)1.26 (1.11, 1.43)1.21 (1.07, 1.37)1.58 (1.44, 1.74)
  1. Model 1: Adjusted for age, sex, and race
  2. Model 2: Adjusted for age, sex, race, height, education, field center, body mass index, smoking, drinking status, diabetes, heart failure, coronary heart disease, and stroke
  3. JNC 7 7th Joint National Committee, ACC/ AHA American College of Cardiology/American Heart Association, PY person-years