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Table 3 Hazard Ratios (95% Confidence intervals) of Atrial Fibrillation According to Hypertension Defined According to JNC 7 and 2017 ACC/AHA Guidelines, ARIC 1987–2015

From: Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study

JNC 7No hypertensionHypertension
No. of AF cases16651226
No. of participants98685047
Incidence rate (per 1000 PY)7.512.5
Model 1 [HR (95%CI)]1 (ref.)1.70 (1.57, 1.83)
Model 2 [HR (95%CI)]1 (ref.)1.44 (1.32, 1.56)
2017 ACC/AHANo hypertensionHypertension
No. of AF cases12831608
No. of participants78117104
Incidence rate (per 1000 PY)7.311.2
Model 1 [HR (95%CI)]1 (ref.)1.55 (1.43, 1.67)
Model 2 [HR (95%CI)]1 (ref.)1.37 (1.26, 1.48)
  1. Model 1: Adjusted for age, sex, and race
  2. Model 2: Adjusted for age, sex, race, height, education, field center, body mass index, smoking, drinking status, diabetes, heart failure, coronary heart disease, and stroke
  3. JNC 7: 7th Joint National Committee, ACC/ AHA American College of Cardiology/American Heart Association, PY person-years