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Table 3 Hazard Ratios (95% Confidence intervals) of Atrial Fibrillation According to Hypertension Defined According to JNC 7 and 2017 ACC/AHA Guidelines, ARIC 1987–2015

From: Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study

JNC 7No hypertensionHypertension
No. of AF cases16651226
No. of participants98685047
Person-years220,59198,426
Incidence rate (per 1000 PY)7.512.5
Model 1 [HR (95%CI)]1 (ref.)1.70 (1.57, 1.83)
Model 2 [HR (95%CI)]1 (ref.)1.44 (1.32, 1.56)
2017 ACC/AHANo hypertensionHypertension
No. of AF cases12831608
No. of participants78117104
Person-years175,925143,092
Incidence rate (per 1000 PY)7.311.2
Model 1 [HR (95%CI)]1 (ref.)1.55 (1.43, 1.67)
Model 2 [HR (95%CI)]1 (ref.)1.37 (1.26, 1.48)
  1. Model 1: Adjusted for age, sex, and race
  2. Model 2: Adjusted for age, sex, race, height, education, field center, body mass index, smoking, drinking status, diabetes, heart failure, coronary heart disease, and stroke
  3. JNC 7: 7th Joint National Committee, ACC/ AHA American College of Cardiology/American Heart Association, PY person-years