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Table 3 Hazard Ratios (95% Confidence intervals) of Atrial Fibrillation According to Hypertension Defined According to JNC 7 and 2017 ACC/AHA Guidelines, ARIC 1987–2015

From: Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study

JNC 7

No hypertension

Hypertension

No. of AF cases

1665

1226

No. of participants

9868

5047

Person-years

220,591

98,426

Incidence rate (per 1000 PY)

7.5

12.5

Model 1 [HR (95%CI)]

1 (ref.)

1.70 (1.57, 1.83)

Model 2 [HR (95%CI)]

1 (ref.)

1.44 (1.32, 1.56)

2017 ACC/AHA

No hypertension

Hypertension

No. of AF cases

1283

1608

No. of participants

7811

7104

Person-years

175,925

143,092

Incidence rate (per 1000 PY)

7.3

11.2

Model 1 [HR (95%CI)]

1 (ref.)

1.55 (1.43, 1.67)

Model 2 [HR (95%CI)]

1 (ref.)

1.37 (1.26, 1.48)

  1. Model 1: Adjusted for age, sex, and race
  2. Model 2: Adjusted for age, sex, race, height, education, field center, body mass index, smoking, drinking status, diabetes, heart failure, coronary heart disease, and stroke
  3. JNC 7: 7th Joint National Committee, ACC/ AHA American College of Cardiology/American Heart Association, PY person-years