Table 1 Results of Work-up Preceding Hospital Admission
Test (Units) | Results from Work-up (Reference Range)a |
|---|---|
Hemoglobin (g/L) | 80 (137–180) |
Mean corpuscular volume (fL) | 84 (82–100) |
Platelets (109/L) | 215 (150–400) |
Leukocyte Count (109/L) | 4.9 (4–11) |
Absolute Neutrophil Count (109/L) | 3.8 (2–8) |
Creatinine (umol/L) | 88 (50–120) |
Aspartate aminotransferase (U/L) | 48 (8–40) |
Alanine aminotransferase (U/L) | 66 (1–60) |
Bilirubin total (umol/L) | 18 (0–24) |
Complement, C3 (g/L) | 0.8 (0.6–1.6) |
Complement, C4 (g/L) | 0.2 (0.1–0.4) |
HIV | Negative |
Brucella | Negative |
Tularensis | Negative |
Yersina | Negative |
Toxoplasmosis | Negative |
Bartonella | Negative |
Syphilis | Negative |
Cytomegalovirus | Negative |
Hepatitis B | Negative |
Hepatitis C | Negative |
Epstein-Barr virus | Negative |
Mycobacterium tuberculosis | Negative |
IgG4 | Negative |
Extractable nucleic antigen | Negative |
Neutrophil cytoplasmic antibodies | Negative |
Rheumatoid factor | Negative |
Anti-cyclic citrullinated peptide antibody (U/mL) | 795 (< 5) |
Serum protein electrophoresis | Normal |
AM cortisol (nmol/L) | 491 (170–500) |
C-reactive peptide (mg/L) | 72 (0–8) |
CT Scan | Numerous non-specific lymphadenopathy. A PET CT scan showed diffuse bilateral axillary, inguinal, mediastinum, abdominal and pelvic lymphadenopathy with no FDG uptake |
Bone marrow biopsy | Minimal monoclonal B cells |
Axillary lymph node biopsy | Inflammation with non-caseating clusters of various cell types with reactive follicular hyperplasia with some features of dermatopathic lymphadenitis and focal granuloma formation |
Skin biopsy | Melanoderma |
Transthoracic Echocardiogram | Mild reduction in left ventricular systolic function with hypokinesis to the inferior basal and mid-segments. Mild right ventricle systolic dysfunction was noted with moderate pulmonary hypertension (RSVP 55 mmHg). No evidence of constrictive pericardium and no significant valvular disease |