Prevalence and risk factors of prolonged corrected QT interval in general Chinese population

Table 5 Multivariate logistic regression analyses of prolonged QTc interval and associated factors after adjusting the clinical diagnosis criteria for gender

Variables	ORs	95% CIs	P-value
Age (per 10 year increase)	1.257	1.164–1.357	< 0.001^*
Female gender	0.497	0.416–0.594	< 0.001^*
Race of Han^a	0.827	0.617–1.109	0.205
Current smoking status	1.015	0.870–1.184	0.847
Current drinking status	1.085	0.905–1.300	0.379
Education
Primary school or below	1.000 (reference)
Middle school	1.010	0.862–1.184	0.900
High school or above	1.014	0.784–1.312	0.916
Physical activity
Low	1.000 (reference)
Moderate	0.896	0.768–1.046	0.164
High	0.652	0.462–0.921	0.015^*
Family income (CNY/year)
≤ 5000	1.000 (reference)
5000–20,000	0.883	0.728–1.073	0.211
> 20,000	0.848	0.680–1.059	0.146
General obesity	1.097	0.842–1.430	0.493
Abdominal obesity	1.191	0.950–1.493	0.130
Hypertension	2.357	2.001–2.775	< 0.001^*
Diabetes	1.638	1.362–1.970	< 0.001^*
High TC	0.865	0.689–1.087	0.214
High TG	1.231	1.033–1.467	0.020^*
High LDL-C	1.111	0.826–1.495	0.486
Low HDL-C	1.143	0.937–1.394	0.187
Calcium (mmol/L) < 1.875	0.830	0.103–6.713	0.861
Potassium (mmol/L) < 3.5	1.957	1.230–3.114	0.005^*
Magnesium (mmol/L) < 0.7	0.590	0.072–4.860	0.624
History of heart disease^b	1.375	1.126–1.678	0.002^*
Medication used^c	1.253	1.085–1.448	0.002^*

*P < 0.05 for the independent association between prolonged QTc interval and each factor after adjusting for the remaining factors
Abbreviations: QTc, corrected QT; OR, odds ratio; 95% CI, 95% confidence interval; CNY, China Yuan (1CNY = 0.15 USD);
TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol
^aCompared with other ethnic minorities in China, such as Mongol and Manchu
^bIncluding coronary heart disease, arrythmia and heart failure
^cIndicating any self-reported medication used in the past two weeks

ISSN: 1471-2261