Prevalence and risk factors of prolonged corrected QT interval in general Chinese population

Table 3 Multivariate logistic regression analyses of prolonged QTc interval and associated factors

Variables	ORs	95% CIs	P-value
Age (per 10 year increase)	1.228	1.168–1.290	< 0.001^*
Female gender	2.878	2.564–3.229	< 0.001^*
Race of Han^a	1.196	0.981–1.458	0.076
Current smoking status	1.075	0.970–1.191	0.166
Current drinking status	0.938	0.821–1.071	0.344
Education
Primary school or below	1.000 (reference)
Middle school	1.075	0.974–1.186	0.151
High school or above	1.157	0.986–1.357	0.073
Physical activity
Low	1.000 (reference)
Moderate	0.925	0.840–1.018	0.11
High	0.832	0.685–1.011	0.064
Family income (CNY/year)
≤ 5000	1.000 (reference)
5000–20,000	0.931	0.815–1.064	0.294
> 20,000	0.926	0.799–1.072	0.302
General obesity	1.043	0.916–1.187	0.528
Abdominal obesity	1.156	1.010–1.324	0.035^*
Hypertension	1.838	1.675–2.016	< 0.001^*
Diabetes	1.593	1.391–1.824	< 0.001^*
High TC	0.977	0.847–1.127	0.747
High TG	1.241	1.104–1.395	0.001^*
High LDL-C	1.112	0.919–1.347	0.276
Low HDL-C	1.119	0.980–1.278	0.096
Calcium (mmol/L) < 1.875	0.667	0.178–2.497	0.547
Potassium (mmol/L) < 3.5	2.636	1.806–3.846	< 0.001^*
Magnesium (mmol/L) < 0.7	0.746	0.200–2.789	0.664
History of heart disease^b	1.065	0.927–1.223	0.375
Medication used^c	1.131	1.036–1.234	0.006^*

*P < 0.05 for the independent association between prolonged QTc interval and each factor after adjusting for the remaining factors
Abbreviations: CNY, China Yuan (1CNY = 0.15 USD); HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride; OR, odds ratio; QTc, corrected QT; 95% CI, 95% confidence interval
^aCompared with other ethnic minorities in China, such as Mongol and Manchu
^bIncluding coronary heart disease, arrythmia and heart failure
^cIndicating any self-reported medication used in the past two weeks

ISSN: 1471-2261