Hospital mortality in acute coronary syndrome: adjustment of GRACE score by D-dimer enables a more accurate prediction in a prospective cohort study

Table 2 Effects of multiple variables on Clinical Outcomes in Univariate and Multivariate Analysis

	Univariate Analysis			Multivariate Analysis
	OR	95% CI	p value	OR	95% CI	p value
GRACE score	1.034	1.028–1.041	<0.001
D-dimer as a continuous variable
D-dimer per 100 ng/mL increase	1.069	1.046–1.093	<0.001	1.060	1.026–1.094	<0.001^a
D-dimer as a categories variable
Low D-dimer group	Reference		<0.001	Reference		0.003
Intermediate D-dimer group	0.689	0.245–1.941	0.481	0.668	0.176–2.532	0.553
High D-dimer group	4.362	2.104–9.044	<0.001	3.079	1.079–8.788	0.036^a

^aAdjusted for age, History of Hypertension, Dyslipidemia, SBP on admission, Heart rate on admission, Diagnosis on admission, Troponin-I, fibrinogen, creatinine, Albumin, Hemoglobin, Leukocyte count, Platelet count, BNP, Left main disease, Three-vessel disease, Use of Intra-aortic Balloon Pump and TIMI flow grade 3 post PCI;

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