Prevalence of left ventricular diastolic dysfunction by cardiac magnetic resonance imaging in thalassemia major patients with normal left ventricular systolic function

Table 4 Intraclass correlation coefficient (n = 10)

Variable	Time 1 Mean ± SD	Time 2 Mean ± SD	Person 2 Mean ± SD	Intraobserver	p-value	Interobserver	p-value
Variable	Time 1 Mean ± SD	Time 2 Mean ± SD	Person 2 Mean ± SD	Time 1 vs. Time 2	p-value	Person 1 vs. Person 2	p-value
EPFR (ml/s)	412.4 ± 105.4	433.6 ± 102.3	448.7 ± 104.9	0.99 (0.97–0.99)	*< 0.001*	0.97 (0.87–0.99)	*< 0.001*
LPFR (ml/s)	224.0 ± 73.8	224.9 ± 80.2	239.3 ± 81.7	0.99 (0.98–0.99)	*< 0.001*	0.97 (0.87–0.99)	*< 0.001*
DT (ms)	159.2 ± 25.8	160.4 ± 27.5	161.4 ± 26.6	0.97 (0.86–0.99)	*< 0.001*	0.94 (0.77–0.99)	*< 0.001*
E velocity (cm/s)	67.6 ± 12.4	67.6 ± 12.4	67.6 ± 12.4	1 (1–1)	NA	1 (1–1)	NA
A velocity (cm/s)	44.7 ± 12.5	44.7 ± 12.5	44.7 ± 12.5	1 (1–1)	NA	1 (1–1)	NA
E/A	1.6 ± 0.6	1.6 ± 0.6	1.6 ± 0.6	1 (1–1)	NA	1 (1–1)	NA
LA area 2ch (mm²)	18.2 ± 3.6	18.7 ± 3.9	18.5 ± 3.6	0.98 (0.93–0.99)	*< 0.001*	0.97 (0.89–0.99)	*< 0.001*
LA length 2ch (mm)	45.0 ± 5.4	44.9 ± 4.9	45.0 ± 5.6	0.95 (0.80–0.99)	*< 0.001*	0.86 (0.55–0.96)	*< 0.001*
LA area 4ch (mm²)	21.6 ± 5.5	22.1 ± 5.1	22.4 ± 4.8	0.98 (0.92–0.99)	*< 0.001*	0.98 (0.92–0.99)	*< 0.001*
LA length 2ch (mm)	55.1 ± 8.1	56.7 ± 8.0	51.2 ± 6.6	0.93 (0.73–0.98)	*< 0.001*	0.88 (0.60–0.97)	*< 0.001*
LA vol (ml)	75.3 ± 25.8	79.2 ± 79.4	79.4 ± 23.5	0.98 (0.91–0.99)	*< 0.001*	0.97 (0.90–0.99)	*< 0.001*
LAVI (ml/m²)	50.0 ± 15.0	52.5 ± 15.5	52.8 ± 13.3	0.97 (0.89–0.99)	*< 0.001*	0.99 (0.87–0.99)	*< 0.001*

A p-value< 0.05 indicates statistical significance (bold and italic)
Intraclass correlation coefficient (ICC) and 95% confidence interval
Abbreviations: EPFR Early peak filling rate, LPFR Late peak filling rate, DT Deceleration time, E velocity Early diastolic filling velocity, A velocity Late atrial systolic filling velocity, E/A E/A ratio, LA area 2ch Left atrial area from 2-chamber view, LA length 2ch Left atrial length from 2-chamber view, LA area 4ch Left atrial area from 4-chamber view, LA length 4ch Left atrial length from 4-chamber view, LA vol Left atrial volume, LAVI Left atrial volume index, NA Not available

ISSN: 1471-2261