Prevalence of left ventricular diastolic dysfunction by cardiac magnetic resonance imaging in thalassemia major patients with normal left ventricular systolic function

Table 3 Univariate and multivariate analysis for factors associated with LV diastolic dysfunction

Factors	Univariate	p-value	Multivariate	p-value
Factors	Crude OR (95% CI)	p-value	Adjusted OR (95% CI)	p-value
Age	1.03 (1.00–1.06)	0.050	1.07 (1.02–1.12)	*0.004*
Body surface area	0.15 (0.02–1.52)	0.108	0.01 (0.0001–0.24)	*0.005*
Splenectomy	2.90 (1.11–7.68)	*0.030*	4.53 (1.29–15.93)	*0.018*
Homozygous beta-thalassemia	5.00 (1.55–16.11)	*0.007*	6.26 (1.38–28.39)	*0.017*
Deferoxamine	0.45 (0.15–1.31)	0.143	–	–
Beta blocker	3.14 (0.65–15.12)	0.153	–	–
Heart rate	0.93 (0.89–0.98)	*0.003*	0.92 (0.87–0.98)	*0.008*
Liver iron concentration	1.03 (0.99–1.07)	0.173	–	–
Diastolic blood pressure	0.95 (0.90–0.99)	*0.017*	0.94 (0.89–0.99)	*0.044*

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