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Table 1 Systemic hemodynamics

From: Cardiac power output accurately reflects external cardiac work over a wide range of inotropic states in pigs

Hemodynamic Parameter Temp. Timepoint RES CME LPS SEVO Dob
HR HT Baseline      98 ± 12.8
(1 min− 1)   After Intervention      122 ± 10.1c
  NT Baseline 89 ± 10.6 89 ± 11.8 97 ± 10 90 ± 14.7 89 ± 13.2
   After Intervention 84 ± 13.2 101 ± 18.5* 128 ± 17.4* 79 ± 9.6* 114 ± 10.2a, c
  MH Baseline 86 ± 16.7 88 ± 10.8 98 ± 11.3 70 ± 10.1 65 ± 8a, b
   After Intervention 59 ± 10.7*† 67 ± 11.4*† 79 ± 11.6*† 60 ± 5.9* 83 ± 11.2a, b, c
MAP HT Baseline      74 ± 8.4
(mmHg)   After Intervention      77 ± 12.3
  NT Baseline 92 ± 11.7 104 ± 17.3 86 ± 4.6 75 ± 7.1 68 ± 8
   After Intervention 64 ± 8.2* 54 ± 13* 53 ± 10.6* 44 ± 4.9* 71 ± 11.8
  MH Baseline 90 ± 8.7 107 ± 10.3 85 ± 5.9 67 ± 7.7 65 ± 7.7a
   After Intervention 73 ± 15.4* 69 ± 6.7*† 58 ± 2.9* 42 ± 3.3* 69 ± 6.5a
CO HT Baseline      6.7 ± 0.9
(L min−1)   After Intervention      8.4 ± 1c
  NT Baseline 5.7 ± 1.2 6.2 ± 0.9 6.8 ± 0.5 6.7 ± 0.6 6.1 ± 1
   After Intervention 4.8 ± 1.1 3.5 ± 0.7* 6.6 ± 1.3 5.0 ± 0,8* 7.8 ± 1.1c
  MH Baseline 5.4 ± 1.3 6.5 ± 0.9 6.2 ± 0.8 4.9 ± 0.6 4.4 ± 0.6 a, b
   After Intervention 3.5 ± 0.7*† 3.2 ± 0.5* 4.5 ± 1.22*† 4.4 ± 0.6 6.0 ± 0.85a, b, c
SVR HT Baseline      842 ± 152
(dyne.sec cm−5)   After Intervention      717 ± 170c
  NT Baseline 1238 ± 401 1292 ± 345 931 ± 76 848 ± 97 856 ± 171
   After Intervention 915 ± 219 1089 ± 256 531 ± 83* 620 ± 117* 703 ± 128c
  MH Baseline 1252 ± 310 1260 ± 153 1018 ± 139 1030 ± 137 1154 ± 202a, b
   After Intervention 1470 ± 384† 1618 ± 252*† 884 ± 206† 675 ± 183* 880 ± 88a, b, c
CPO HT Baseline      1.10 ± 0.2
(W)   After Intervention      1.40 ± 0.3c
  NT Baseline 1.14 ± 0.2 1.43 ± 0.3 1.29 ± 0.1 1.12 ± 0.2 0.90 ± 0.2
   After Intervention 0.69 ± 0.24* 0.42 ± 0.2* 0.80 ± 0.3* 0.48 ± 0.1* 1.20 ± 0.3a, c
  MH Baseline 1.09 ± 0.3 1.55 ± 0.3 1.17 ± 0.2 0.72 ± 0.1 0.60 ± 0.1a, b
   After Intervention 0.58 ± 0.2* 0.49 ± 0.1* 0.58 ± 0.2* 0.40 ± 0.0* 0.90 ± 0.2a, b, c
  1. All values are presented as mean ± standard deviation (SD). Temp. Temperature, HT Hyperthermia, NT Normothermia, MH Mild hypothermia, RES Resuscitation after ventricular fibrillation, CME Coronary microembolisation, LPS Endotoxemia by Lipopolysaccharide (LPS)-infusion, SEVO Sevoflurane-induced myocardial depression, Dob Temperature modulation from hyperthermia to mild hypothermia vs. dobutamine (intervention) at each temperature step, HR Heart rate, MAP Mean aortic pressure, CO Cardiac Output, SVR Systemic vascular resistance, CPO Cardiac Power Output
  2. *p < 0.05 vs baseline; †p < 0.05 vs NT; ap < 0.05 vs hyperthermia; bp < 0.05 vs normothermia; cp < 0.05 vs baseline at each temperature step
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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