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Table 5 Cox regression analysis results

From: Going beyond classic echo in aortic stenosis: left atrial mechanics, a new marker of severity

Outcomes Predictors HR (95%CI) P value
Heart failure LA-SRs 0.17 (0.1-0.8) 0.022
GLS 1.11 (1.0-1.3) 0.045
BNP 1.0 (0.9-1.01) 0.810
E/e’ ratio 1.0 (0.9-1.1) 0.710
TAPSE 0.96 (0.84-1.1) 0.522
RV/RA gradient 1.0 (0.9-1.1) 0.667
Aortic valve replacement Mean gradient 1.40 (1.1-1.6) < 0.001
AVA 0.04 (0.01-0.14) < 0.001
LA ɛsys 0.95 (0.91-0.99) 0.027
LA ɛe 0.91 (0.85-0.98) 0.026
Death BNP 1.2 (1.0-1.3) 0.002
LA ɛe 0.84 (0.74-0.96) 0.010
GLS 1.22 (1.08-1.41) 0.003
Combined outcome LV-GLS (%) 1.16 (1.08-1.23) < 0.001
LA ɛsys (%) 0.9 (0.92-0.93) < 0.001
Global strain 0.95 (0.93-0.98) 0.035
E/e’ ratio 1.01 (0.97-1.04) 0.667
TAPSE (mm) 0.97 (0.01-1.03) 0.414
RV/RA gradient 1.01 (0.98-1.04) 0.285
  1. LA ɛsys left atrial systolic strain (reservoir function), LA ɛe left atrial early diastolic strain (conduit function), LA ɛa left atrial late diastolic strain (contractile function), LA SRs left atrial systolic strain rate (reservoir function), LA SRe left atrial early diastolic strain rate (conduit function), LA SRa left atrial late diastolic strain (contractile function), LV-GLS left ventricular global longitudinal strain, RV/RA gradient right ventricle/right atrium gradient, TAPSE tricuspid annular plane systolic excursion