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Table 2 Discriminative power of echocardiographic parameters according to aortic stenosis severity

From: Going beyond classic echo in aortic stenosis: left atrial mechanics, a new marker of severity

  AUC 95% CI P-value Sensitivity (%) Specificity (%) Criterion
LA ɛsys (%) 0.870 0.799–0.923 < 0.001 85.0 64.1 11
LA ɛe (%) 0.824 0.747–0.886 < 0.001 88.7 73.4 9.4
LA ɛa (%) 0.810 0.732–0.874 < 0.001 86.6 76.6 18.5
Global strain (%) 0.809 0.735–0.870 < 0.001 69.6 85.9 0.56
LA SRs (%) 0.707 0.626–0.779 < 0.001 41.5 90.6 0.64
LA SRe (%) 0.645 0.556–0.728 0.001 71.9 56.1 0.28
LA SRa (%) 0.628 0.538–0.712 0.006 50.7 75.0 −1
IVS (mm) 0.623 0.540–0.702 0.001 46.3 76.6 12
LV-GLS (%) 0.606 0.516–0.691 0.056 77.2 37.5 −20
LAVI (mL.m−2) 0.593 0.508–0.675 0.054 59.8 62.5 39.7
E/e’ ratio 0.588 0.493–0.678 0.097 31.8 90.6 21.5
TAPSE (mm) 0.543 0.458–0.627 0.427 42.5 75 18
PASP (mmHg) 0.531 0.446–0.615 0.517 41.8 73.4 23
  1. AUC area under the curve, IVS interventricular septum, LAVI left atrial volume (indexed), LA ɛsys left atrial systolic strain (reservoir function), LA ɛe left atrial early diastolic strain (conduit function), LA ɛa left atrial late diastolic strain (contractile function), LA SRs left atrial systolic strain rate (reservoir function), LA SRe left atrial early diastolic strain rate (conduit function), LA SRa left atrial late diastolic strain (contractile function), LV-GLS left ventricular global longitudinal strain, PASP pulmonary artery systolic pressure, TAPSE tricuspid annular plane systolic excursion