Going beyond classic echo in aortic stenosis: left atrial mechanics, a new marker of severity

Table 2 Discriminative power of echocardiographic parameters according to aortic stenosis severity

	AUC	95% CI	P-value	Sensitivity (%)	Specificity (%)	Criterion
LA ɛsys (%)	0.870	0.799–0.923	< 0.001	85.0	64.1	11
LA ɛe (%)	0.824	0.747–0.886	< 0.001	88.7	73.4	9.4
LA ɛa (%)	0.810	0.732–0.874	< 0.001	86.6	76.6	18.5
Global strain (%)	0.809	0.735–0.870	< 0.001	69.6	85.9	0.56
LA SRs (%)	0.707	0.626–0.779	< 0.001	41.5	90.6	0.64
LA SRe (%)	0.645	0.556–0.728	0.001	71.9	56.1	0.28
LA SRa (%)	0.628	0.538–0.712	0.006	50.7	75.0	−1
IVS (mm)	0.623	0.540–0.702	0.001	46.3	76.6	12
LV-GLS (%)	0.606	0.516–0.691	0.056	77.2	37.5	−20
LAVI (mL.m⁻²)	0.593	0.508–0.675	0.054	59.8	62.5	39.7
E/e’ ratio	0.588	0.493–0.678	0.097	31.8	90.6	21.5
TAPSE (mm)	0.543	0.458–0.627	0.427	42.5	75	18
PASP (mmHg)	0.531	0.446–0.615	0.517	41.8	73.4	23

AUC area under the curve, IVS interventricular septum, LAVI left atrial volume (indexed), LA ɛsys left atrial systolic strain (reservoir function), LA ɛe left atrial early diastolic strain (conduit function), LA ɛa left atrial late diastolic strain (contractile function), LA SRs left atrial systolic strain rate (reservoir function), LA SRe left atrial early diastolic strain rate (conduit function), LA SRa left atrial late diastolic strain (contractile function), LV-GLS left ventricular global longitudinal strain, PASP pulmonary artery systolic pressure, TAPSE tricuspid annular plane systolic excursion

ISSN: 1471-2261