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Table 6 Comparison of fasting lipid profile between subjects carrying E3/E3 and ε 4 allele

From: Apolipoprotein E gene polymorphism and the risk of cardiovascular disease and type 2 diabetes

Variables (mg/dL) Control T2DM CVD CVD + T2DM+
E3/E3 ε4 E3/E3 ε4 E3/E3 ε4 E3/E3 ε4
TC 4.30 ± 1.36 4.35 ± 1.19 5.58 ± 1.56 5.73 ± 2.03 4.98 ± 1.17 5.38 ± 1.21* 4.97 ± 1.36 5.20 ± 1.30
TG 1.53 ± 1.60 1.73 ± 1.65 2.51 ± 3.40 3.23 ± 3.81 1.40 ± 0.82 1.98 ± 1.33** 2.12 ± 1.49 2.81 ± 2.17**
LDL-C 2.31 ± 0.91 2.39 ± 0.91 3.15 ± 1.00 3.12 ± 1.35 2.81 ± 0.90 3.10 ± 0.84* 2.71 ± 1.00 2.99 ± 0.97
HDL-C 1.25 ± 0.43 1.24 ± 0.37 1.27 ± 0.36 1.19 ± 0.29 1.32 ± 0.32 1.23 ± 0.35 1.21 ± 0.29 1.09 ± 0.35**
ApoA1 1.03 ± 0.33 1.09 ± 0.28 1.18 ± 0.34 1.13 ± 0.28 1.13 ± 0.27 1.05 ± 0.28 1.14 ± 0.32 1.02 ± 0.29*
ApoB 0.72 ± 0.26 0.77 ± 0.33 0.97 ± 0.31 0.99 ± 039 0.83 ± 0.27 0.88 ± 0.22* 0.88 ± 0.30 0.93 ± 0.32
  1. ε4 = E3/E4, E4/E4
  2. Independent sample t-test test was applied to compare between E3/E3 and ε4 allele. Data are presented as mean ± SD