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Table 5 APOE polymorphism and the risk of T2DM and CVD represented as adjusted OR

From: Apolipoprotein E gene polymorphism and the risk of cardiovascular disease and type 2 diabetes

Variables

T2DM

CVD

T2DM + CVD

Adjusted OR (95% CI)

p

Adjusted OR (95% CI)

p

Adjusted OR (95% CI)

p

ε4

1.62 (0.87–3.03)

0.13

1.78 (0.87–3.67)

0.12

3.69 (1.94–6.99)

0.00

Age

1.08 (1.05–1.11)

0.00

1.10 (1.06–1.14)

0.00

1.16 (1.12–1.20)

0.00

Sex

1.11 (0.68–1.83)

0.67

2.25 (1.11–4.56)

0.02

1.18 (0.67–2.09)

0.57

Smoking

3.39 (1.65–7.00)

0.00

7.10 (2.74–18.40)

0.00

9.64 (4.26–21.83)

0.00

SBP (mmHg)

1.03 (1.02–1.05)

0.00

1.00 (0.98–1.02)

0.84

1.02 (1.00–1.04)

0.02

DBP (mmHg)

0.99 (0.97–1.02)

0.62

1.00 (0.97–1.03)

0.83

1.01 (0.98–1.04)

0.48

  1. After adjusting for age, sex, smoking state, SBP (mmHg), DBP (mmHg). Normal reference ranges of clinical and biochemical data are described in materials and method