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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Fig. 4

Associations of a PCSK9 gene-centric score (GS) with non-cardiovascular events. Footnote: Effect estimates are presented as odds ratios (OR), with 95% confidence interval (CI) scaled to a 1 mmol/L lower LDL-C (mmol/L). Results are pooled using a fixed effect model. The size of the squares are proportional to the inverse of the variance. Note, that all GS estimates are based on 4 SNPs, except for the Alzheimer’s disease estimate which excluded the SNP rs11591147 due to lack of data

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