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Table 3 The risk of rs7819412 for CAD and ischemic stroke according to body mass index (BMI), gender, smoking and drinking

From: Association between the XKR6 rs7819412 SNP and serum lipid levels and the risk of coronary artery disease and ischemic stroke

Factors

Genetype

CAD

Ischemic stroke

OR (95%CI)

P

P interaction

OR (95%CI)

P

P interaction

BMI

  < 24 Kg/m2

GG

1

 

0.000

1

 

0.006

GA/AA

1.229 (0.841–1.795)

0.287

 

1.179 (0.793–1.753)

0.416

 

  ≥ 24 Kg/m2

GG

1

  

1

  

GA/AA

2.174 (1.227–3.756)

0.007

 

1.731 (1.048–2.858)

0.032

 

Gender

 Male

GG

1

 

0.058

1

 

0.735

GA/AA

1.448 (1.034–2.141)

0.032

 

1.483 (1.023–2.148)

0.037

 

 Female

GG

1

  

1

  

GA/AA

1.250 (0.725–2.153)

0.422

 

1.243 (0.719–2.151)

0.436

 

Smoking

 Nonsmoker

GG

1

 

0.000

1

 

0.014

GA/AA

1.185 (0.813–1.727)

0.378

 

1.205 (0.823–1.765)

0.338

 

 Smoker

GG

1

  

1

  

GA/AA

2.630 (1.593–4.342)

0.000

 

1.925 (1.137–3.257)

0.015

 

Drinking

 Nondrinker

GG

1

 

0.481

1

 

0.126

GA/AA

1.238 (0.859–1.784)

0.253

 

1.266 (0.876–1.830)

0.210

 

 Drinker

GG

1

  

1

  

GA/AA

1.737 (0.993–3.037)

0.053

 

1.514 (0.943–2.672)

0.152

 
  1. CAD coronary artery disease