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Table 1 Comparison of demographic, lifestyle characteristics and serum lipid levels of the participants

From: Association between the XKR6 rs7819412 SNP and serum lipid levels and the risk of coronary artery disease and ischemic stroke

Characteristic

Control

(n = 643)

Case

P vs. controls

CAD

(n = 588)

Ischemic stroke

(n = 552)

P CAD

P Ischemic stroke

Male/female

473/170

432/156

400/152

0.936

0.670

Age (years)

61.61 ± 11.95

62.32 ± 10.53

62.73 ± 12.37

0.270

0.111

Height (cm)

155.08 ± 7.84

164.11 ± 6.97

163.88 ± 7.12

0.000

0.000

Weight (kg)

54.56 ± 9.00

64.50 ± 10.68

63.14 ± 11.04

0.000

0.000

BMI (kg/m2)

22.66 ± 3.19

23.87 ± 3.24

23.44 ± 3.45

0.000

0.000

Smoking, n %

250 (38.8)

248 (42.2)

230 (41.7)

0.239

0.327

Alcohol, n %)

277 (43.1)

133 (22.6)

156 (28.3)

0.000

0.000

SBP (mmHg)

128.05 ± 19.00

132.93 ± 23.40

147.86 ± 21.89

0.000

0.000

DBP (mmHg)

80.41 ± 11.42

79.25 ± 14.15

83.84 ± 12.79

0.111

0.000

PP (mmHg)

47.64 ± 13.97

53.68 ± 17.54

64.02 ± 17.75

0.000

0.000

Glu (mmol/L)

6.01 ± 1.60

6.25 ± 1.48

6.20 ± 1.45

0.008

0.037

TC (mmol/L)

4.34 ± 1.05

4.55 ± 1.22

4.54 ± 1.16

0.001

0.002

TG (mmol/L)

1.38 ± 1.77

1.65 ± 1.11

1.68 ± 1.46

0.001

0.002

HDL-C (mmol/L)

1.90 ± 0.49

1.15 ± 0.34

1.23 ± 0.41

0.000

0.000

LDL-C (mmol/L)

2.72 ± 0.77

2.86 ± 1.02

2.83 ± 0.91

0.009

0.029

ApoA1 (g/L)

1.42 ± 0.27

1.03 ± 0.35

1.03 ± 0.23

0.000

0.000

ApoB (g/L)

0.90 ± 0.21

0.91 ± 0.27

0.89 ± 0.24

0.588

0.507

ApoA1/ApoB

1.65 ± 0.56

1.24 ± 0.80

1.25 ± 0.50

0.000

0.000

  1. SBP Systolic blood pressure, DBP Diastolic blood pressure, PP Pulse pressure, Glu Glucose, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Apo Apolipoprotein, TC Total cholesterol, TG Triglyceride. The value of triglyceride was presented as median (interquartile range), the difference between the control and CAD/Ischemic stroke groups was determined by the Wilcoxon-Mann-Whitney test