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Table 1 Literature review of 101 cases of Swallow Syncope from 1949 to 2018

From: Swallow syncope: a case report and review of literature

Author/ Reference

Age/ Gender

Presenting Symptom

Underlying Diseases

Trigger Factor

Type of arrhythmia

Management

Effectiveness

Padalia et al. 2018/ [6]

65/ F

Presyncope, Dysphagia, Odynophagia/

Candida Esophagitis, Metabolic Diseases

Solid and Liquid

Sinus bradycardia, Sinus arrest

Micafugin

Yes

Sammy et al. 2018/ [7]

67/M

Syncope

End Stage Renal Failure

Ascension of Hyoid bone irritate carotid sinus

Yamaguchi et al. 2018/ [8]

76/M

Syncope

No

Solid and Liquid (Citrus based)

Sinus arrest, AV block

PPM

Yes

Lipar et al. 2018/ [9]

49/F

Syncope

Post whiplash neck injury

Solid and Liquid

PPM

Yes

Van Damme et al. 2017/ [10]

39/M

Syncope

No

Solid and Liquid

3rd degree AV block

PPM

Aydogdu et al. 2017/ [11]

51/F

Presyncope, Syncope

No

Solid food

AV block

Rejected PPM

65/F

Syncope

Liquid (Carbonated)

Sinus arrest, 3rd degree AV block

PPM

Yes

39/F

Presyncope, Syncope

No

Solid food

3rd degree AV block

PPM

Yes

53/F

Presyncope, Syncope

No

Solid food

Asystole

Diet modification

68/M

Presyncope, Syncope

Atrial Fibrillation

Liquids

Asystole

PPM

Yes

Patel et al. 2017/ [12]

48/M

Syncope, Nausea, Tunnel vision

Hiatus Hernia

Solid and Liquid

Sinus arrest

Hiatus hernia repair surgery

Yes

Zaid et al. 2017/ [13]

71/M

Syncope

Achalasia

Solid food

AV block

Bhogal et al. 2017/ [14]

68/F

Presyncope

Hiatus Hernia, Metabolic Diseases

Solid food

Sinus Bradycardia, 1st degree AV block

Discontinuation of metoprolol + Proton Pump Inhibitor

No

59/M

Pre-syncope & Syncope

No

Liquid diet

Premature atrial complexes & Asystole

PPM

Yes

Trinco et al. 2016/ [15]

83/ M

Syncope

Carotid endarterectomy, Metabolic diseases

Solid and Liquid

Sinus bradycardia, 3rd degree AV block

PPM

Yes

Islam et al. 2016/ [16]

60/ F

Presyncope, Syncope

No

Solid food (Large chunk of bread)

AV block

Avoidance of trigger

Yes

Chhetri et al. 2016/ [17]

71/M

Syncope

Fundoplication for GERD

Solid and Liquid (Fizzy drink)

Sinus arrest

PPM

NM

Tiffany et al. 2016/ [18]

80/F

Syncope, palpation, facial flushing

Metabolic diseases, Hypothyrodism

Solid and Liquid

Atrial Tachycardia

Catheter ablation

Yes

Manu et al. 2016/ [19]

13/F

Syncope

Superior sinus atrial septal defect

Solid and Liquid

3rd degree AV block

PPM

Yes

Aaberg et al. 2015/ [20]

62/M

Pre-syncope, Syncope

No

Solid and Liquid

2nd and 3rd degree AV block

PPM

Yes

Kahn et al. 2015/ [4]

89/M

Syncope

Transient Oesophageal dysmotility, Coronary artery diseases

Solid and Liquid (Carbonated)

1st and 2nd degree AV block

PPM

Yes

Saitoh et al. 2015/ [21]

70/M

Syncope

No

Solid food

Asystole

PPM

Yes

Erdogan et al. 2015/ [22]

47/M

Syncope

Achalasia

Solid and Liquid

AV block, Asystole

Pneumatic dilation

Yes

Shashank et al. 2014/ [23]

31/F

Presyncope & Syncope

No

Liquid (Carbonated)

Sinus bradycardia, Asystole

PPM

Yes

78/ M

Presyncope

Sick sinus syndrome, Metabolic diseases

Solid food

PPM + Coffee before meals

Yes

80/M

Presyncope, Syncope

Hiatus Hernia AF, various cardiac comorbid

Solid food (Sticky food)

Avoidance of trigger

Yes

Shah et al. 2014/ [24]

57/M

Presyncope, Syncope

No

Swallow +Cold drink

Advanced heart block for 3–4 s

PPM

Yes

Witcik et al. 2014/ [25]

70/M

Syncope, Weakness, Flushing

Mild AV regurgitation

Liquid (Carbonated)

Atrial Fibrillation with ventricular pause

PPM

Yes

Arihide et al. 2014/ [26]

79/M

Syncope

Coronary artery disease, Metabolic diseases

Solid and Liquid

Sinus arrest

PPM

Yes

Moore et al. 2013/ [27]

65/F

Presyncope, Syncope

No

Solid food

AV block

PPM

Yes

Lambiris et al. 2013/ [28]

54/M

Presyncope, Shortness of breath

No

Solid and Liquid

1st degree AV block

PPM

Yes

Rezvani et al. 2013/ [29]

51/F

Syncope

Post Laparoscopic gastrectomy

Solid and Liquid

AV block

Atropine

Yes

Kim eat al. 2012/ [30]

39/M

Syncope, Chest tightness

No

Liquid (Cold)

3rd degree AV block

Avoidance of trigger

Yes

Knopke et al. 2012/ [31]

49/F

Syncope, Dysphagia, Regurgitation

Hiatus hernia, Diffuse oesophageal spasm

Solid food

3rd degree AV block

PPM

Yes

Foreman et al. 2011/ [32]

52/F

Presyncope, Chest pain

No

Solid food

2nd degree AV block

PPM

Yes

Vanerio et at. 2011/ [33]

84/F

Syncope

Hiatus Hernia

Solid and Liquid (Carbonated)

Nissen’s Fundoplication

Yes

Mitra et al. 2011/ [34]

60/F

Presyncope, Syncope

Metabolic Diseases

Solid food

Sinus Bradycardia, 3rd degree AV block

PPM

Yes

Marina et al. 2010/ [35]

37/M

Syncope

Megaoesophagus, Extra Cardiac mass compressing left atrium

Solid and Liquid

Deflation of gastric band

GY Lee et al. 2010/ [36]

62/M

Syncope, Dysphagia

Atrial Fibrillation, Metabolic diseases

Liquid

Asystole

PPM

Yes

Endean et al. 2010/ [37]

61/ M

Syncope, Chest pain, Vision lost

Post Carotid entaterectomy

Solid food

Glycopyrrolate

Yes

Casella et al. 2009/ [38]

66/ M

Syncope

Oesophageal dysmotility, Sick sinus syndrome

Liquid only

AV block

PPM

Yes

Karamitsos et al. 2009/ [39]

82/F

Syncope

Hiatus hernia

Large meal

NM

Favaretto et al. 2008/ [40]

63/M

Syncope, Odynophagia

Hiatus hernia

Solid and Liquid

Asystole

PPM

Yes

Bajwa et al. 2008/ [41]

51/M

Presyncope, Syncope

Metabolic diseases, Inflammatory bowel diseases

Solid food

Atrial & Ventricular atopic beat

PPM

Yes

Christopher et al. 2008/ [42]

25/F

Syncope

No

Solid and Liquid

3rd degree AV block

PPM

Yes

Fahrner et al. 2008/ [43]

75/M

Syncope

No

Solid and Liquid

AV block

Patsilinakos et al. 2007/ [44]

86/F

Syncope

Oesophageal stenosis, Ascending aorta aneurysm, Hypothyroidism

Solid and Liquid

Sinus arrest

Avoidance of trigger

Yes

Tuzcu et al. 2007/ [45]

16/F

Syncope, Visual disturbance

No

Solid food

3rd degree AV block, Asystole

PPM

Yes

Omni et al. 2006/ [2]

66/F

Syncope

Metabolic Diseases

Liquid

AV block

PPM

Yes

Gawrieh et al. 2005/ [46]

63/M

Presyncope, Syncope, Dysphagia

Hiatus Hernia

Solid food

AV block, Asystole

PPM

Yes

63/M

Presyncope, Syncope

Hiatus hernia, Coronary artery diseases, Metabolic diseases

Solid and Liquid

Refuse treatment

62/F

Presyncope, Syncope, Dysphagia

Nutcracker oesophagus, Coronary artery diseases

Solid and Liquid

Sinus bradycardia, Sinus arrest

PPM

Yes

Turan et al. 2005/ [47], Kang et al. 2005/ [48]

48/M

Syncope, Dysphagia

Achalasia

Solid food

Sinus bradycardia

PPM

Yes

59/ M

Syncope

Metabolic diseases

Solid and Liquid

Sinus bradycardia

PPM

59/M

Syncope, Dysphagia

Compression fracture thoracic spine, Graves diseases

Solid food

Sinus bradycardia

Diet habit modification

Sreekant et al. 2004/ [49]

85/M

Syncope

Coronary artery diseases, Peripheral vascular diseases

Solid and liquid

Asystole

PPM

Yes

61/ F

Presyncope

Metabolic diseases

Liquid (Carbonated)

Sinus Bradycardia

Yoshifumi et al. 2004/ [50]

76/F

Syncope

Hiatus hernia

Solid food

Srivathsan et al. 2003/ [51]

26/M

Presyncope

No

Solid food

Systole

PPM

Yes

Mekawa et al. 2002/ [52]

76/ F

Syncope

Hiatus hernia

Solid and liquid

Hernia repair surgery

Yes

Gordon et al. 2002/ [53]

26/F

Syncope, Central chest discomfort

Hiatus hernia

Solid and liquid

Paroxysmal Atrial fibrillation, Ventricle atopic beat

Diet habit modification

Yes

Takeshi et al. 2002 [54]

69/F

Presyncope, Syncope

Metabolic diseases

Solid food

Sinus arrest

Rasmi et al. 2001/ [55]

16/M

Syncope

No

Liquid (Carbonated)

Asystole

PPM

Yes

Haumer et al. 2000/ [56]

67/ M

Syncope

Coronary artery disease

Liquid

Sinus arrest

Temporary Pacemaker

Yes

Kakuchi et al. 2000/ [57]

21/M

Syncope

Vasovagal syncope

Solid and liquid

AV block

PPM

Kazushi et al. 1999/ [58]

69/M

Syncope, Facial flushing, Profuse diarrhoea

Metabolic disease, Stroke

Solid food

Cessation of Enalapril

Yes

Olshasky et al. 1999/ [59]

72/M

Presyncope, Syncope

Liquid (Cold carbonated)

Sinus bradycardia

PPM

Dante et al. 1997/ [60]

78/M

Syncope

Oesophageal carcinoma

Solid food

AV block, Asystole

PPM

Yes

Bellori et al. 1992/ [61]

69/M

Syncope

Liquid

Sinus arrest

SY AO et al. 1991/ [5]

70/M

Incidental

Lung carcinoma

Solid and Liquid

High grade AV block

Atropine before meal

Yes

Shapira et al. 1991/ [62]

63/M

Presyncope, Syncope

Hiatus hernia, Coronary artery disease

Solid and Liquid

2nd degree AV block

PPM

Yes

Kunimoto et al. 1990/ [63]

65/M

Presyncope, Syncope

No

Liquid (Cold)

2nd degree AV block, Asystole

PPM

Yes

Elam et al. 1989/ [64]

44/M

Syncope

No

Solid and Liquid

3rd degree AV block

PPM

Yes

Engelharbt et al. 1986/ [3]

5/F

Syncope

No

Solid and Liquid/ Brush teeth

3rd degree AV block

Close Observation

Yes

Ausubel et al. 1987/ [65]

26/M

Syncope

Heart murmur

Solid food

Sinus bradycardia, AV block

PPM

Yes

Nakano et al. 1987/ [66]

67/M

Syncope, Retrosternal discomfort

Aneurysm descending thoracic aorta

Solid and Liquid

Sinus bradycardia, Sinus arrest

Atropine before meal

Yes

Nakagawa et al. 1987/ [67], Guberman et al.1986/ [68]

48/M

Syncope

No

Solid and Liquid

AV block

Atropine

62/F

Syncope

No

Oesophageal balloon inflation

2nd degree heart block

Propanthelene bromide

No

62/M

Syncope

Congestive heart failure

Solid food

2nd degree heart block

Discontinuation of digoxin

Yes

Alan et al. 1986/ [69]

56/M

Syncope

Inferior myocardial infarction

Liquid

1st degree heart block

PPM

Yes

Golf et al. 1986/ [70]

15/ F

Syncope

No

Solid and Liquid

SA node blockade with junctional escape rhythm

Armstrong et al. 1985/ [71]

53/F

Syncope, Dyspnoea, Retrosternal discomfort

Hiatus hernia

Liquid

Sinus bradycardia

PPM

Yes

58/F

Syncope, Pulseless, Apnoea

Myocardial infarction, Atrial Fibrillation, Stroke

Solid and Liquid

Sinus bradycardia and Asystole

PPM

No

58/F

Presyncope

No

Solid and Liquid

3rd degree AV block and Asystole

PPM

Yes

81/F

Syncope

Hiatus hernia, Metabolic disease

Liquid (Hot)

Sinus bradycardia

PPM

Yes

53/M

Syncope

Myocardial infarction

Liquid (Cold)

2nd degree AV block

PPM

Yes

Kunis et al. 1985/ [72]

60/M

Presyncope, Syncope, Chest pain

Metabolic diseases

Solid food (Hot)

3rd degree AV block, Asystole

PPM

Yes

Drake et al. 1985/ [73]

76/F

Syncope

Myocardial infarction, Metabolic disease

Sight of food

3rd degree AV block

PPM

Yes

Mauro et al. 1985/ [74]

65/ F

Presyncope, syncope

Myocardial ischemia

Solid and Liquid

2nd degree AV block

Atropine

No

Golf et al. 1977 [75]

−/ M

Syncope, Convulsion

No

Solid and Liquid

2nd degree AV block

PPM

Yes

Weaddington et al. 1975/ [76]

71/M

Syncope

Hiatus hernia, Oesophagus carcinoma, Atrial Fibrillation

Solid food

Sinus bradycardia and Asystole

Surgical removal of Oesophageal Carcinoma

Yes

B Wik et al. 1975/ [77]

43/ M

Syncope, Retrosternal chest pain

Rheumatic heart diseases

Liquid (Carbonated)

AV block

PPM

Poul et al. 1973/ [78]

64/ F

Syncope

Hiatus hernia, Abnormal oesophageal motility

Solid and Liquid

Sinus bradycardia, AV block

Hernia Repair

Yes

Edgar et al. 1972/ [79]

84/M

Syncope

Hiatus hernia, Metabolic diseases

Solid and Liquid

2nd degree AV block

Atropine

Yes

Keith et al. 1971/ [80]

45/M

Syncope, Dysphagia, Heart burn

Hiatus hernia, Oesophageal stricture

Solid and Liquid

Sinus bradycardia

Dilation of oesophageal stricture

Yes

Rajendra et al. 1971/ [81]

29/ F

Syncope

No

Solid and Liquid

Asystole

Surgical cauterization vagal nerve

Yes

Edgardo et al. 1970/ [82]

73/M

Syncope, Chest pain

Myocardial infarction, Metabolic disease

Solid and Liquid

AV block, Asystole

Atropine

Yes

R P Sapru et al.1968/ [83]

29/F

Presyncope

No

Solid and Liquid

AV block, Asystole

Atropine

Yes

George et al. 1958/ [84]

−/−

Syncope

No

Liquid

Discontinuation of digitalis

Yes

Correll et al. 1949/ [85]

67/M

Syncope, Chocking sensation

Oesophageal diverticulum, Digitalis medication

Solid and Liquid

3rd degree AV block

Atropine

Yes

  1. F Female, M Male, (−) Not Stated, AV Atrioventricular, PPM Permanent Pacemaker