Table 1 Baseline characteristics of patients who undergoing PCI
Variable | Total (n = 531) | ISR (n = 183) | no-ISR (n = 348) | p-value |
|---|---|---|---|---|
Age, years | 59.4 ± 9.8 | 58.8 ± 9.8 | 60.5 ± 9.8 | 0.069 |
Male, n (%) | 350 (65.9) | 114 (62.3) | 236 (67.4) | 0.202 |
Follow-up period, days | 363 (289–386) | 364 (294–391) | 363 (285–385) | 0.471 |
Risk factors, n (%) | ||||
Cigarette smoking | 143 (26.9) | 42 (23) | 101 (29) | 0.134 |
Alcohol drinking | 96 (18.1) | 29 (15.8) | 67 (19.3) | 0.332 |
Hypertension | 247 (46.5) | 92 (50.3) | 155 (44.5) | 0.208 |
Diabetes mellitus | 115 (21.7) | 49 (26.8) | 66 (19.0) | 0.038 |
Hyperlipemia | 31 (5.8) | 6 (3.3) | 25 (7.2) | 0.068 |
Biochemical tests | ||||
Thrombocytocrit, mmol/L | 0.19 ± 0.07 | 0.18 ± 0.04 | 0.19 ± 0.08 | 0.041 |
MPV, fl | 9.03 ± 3.0 | 8.85 ± 1.7 | 9.12 ± 3.5 | 0.338 |
HBA1C, % | 6.23 ± 1.9 | 6.53 ± 1.9 | 6.07 ± 1.9 | 0.007 |
Glucose, mmol/L | 5.43 ± 1.9 | 5.6 ± 1.9 | 5.35 ± 1.9 | 0.16 |
Serum creatinine, μmol/L | 75.7 ± 35.2 | 71.8 ± 22.4 | 77.8 ± 40.2 | 0.06 |
TC, mmol/L | 3.82 ± 1.1 | 3.79 ± 1.1 | 3.83 ± 1.2 | 0.673 |
TG, mmol/L | 1.62 ± 1.1 | 1.59 ± 0.8 | 1.64 ± 1.2 | 0.646 |
HDL, mmol/L | 1.07 ± 0.3 | 1.07 ± 0.3 | 1.07 ± 0.3 | 0.997 |
LDL, mmol/L | 2.3 ± 0.9 | 2.3 ± 0.9 | 2.29 ± 0.9 | 0.895 |
Coronary artery lesions, n (%) | < 0.001 | |||
Single-vessel disease | 225 (42.4) | 64 (35) | 161 (46.3) | |
Double-vessel disease | 168 (31.6) | 49 (26.8) | 119 (34.2) | |
Triple-vessel disease | 138 (26) | 70 (38.3) | 68 (49.3) | |
Medications, n (%) | ||||
Clopidogrel | 420 (79.1) | 156 (85.2) | 264 (75.9) | 0.011 |
Ticagrelor | 119 (22.4) | 37 (20.2) | 82 (23.6) | 0.38 |
Statins | 505 (95.1) | 179 (97.8) | 326 (93.7) | 0.036 |
ACEI/ARB | 196 (37) | 75 (41) | 121 (34.9) | 0.166 |
β-blocker | 383 (72.1) | 133 (72.7) | 250 (71.8) | 0.838 |
CCB | 158 (29.9) | 58 (32) | 100 (28.8) | 0.442 |
Antidiabetic therapy | 264 (49.7) | 99 (54.1) | 165 (47.4) | 0.143 |
Nitrate | 520 (97.9) | 181 (98.9) | 339 (97.4) | 0.251 |
ALDH2 genotype, n (%) | 0.028 | |||
ALDH2 *1/*1 | 365 (68.7) | 115 (62.8) | 250 (71.8) | |
ALDH2 *1/*2 | 151 (28.4) | 59 (32.2) | 92 (26.4) | |
ALDH2 *2/*2 | 15 (2.8) | 9 (4.9) | 6 (1.7) | |