Study of angiotensin-converting enzyme insertion/deletion polymorphism, enzyme activity and oxidized low density lipoprotein in Western Iranians with atherosclerosis: a case-control study

Table 1 Summary of some previous ACE I/D polymorphism studies

Study	Region	Sample size		Genotype frequency in cases			Genotype frequency in controls			P-value
Study	Region	Cases	controls	II	ID	DD	II	ID	DD	P-value
1	Japan [19]	100	178	44	60	74	41	33	26	P < 0.01
2	North Iran [20]	369	141	21	69	51	95	180	94	P = 0.009
3	America [21]	169	132	83	69	17	72	51	9	P < 0.001
4	Asian populations [22]	378	313	133	174	71	114	129	70	p > 0.05
5	Italy [23]	236	158	20	118	98	20	71	67	p < 0.27
6	European population [24]	405	357	64	196	145	70	151	136	NS
7	Turkey [25]	218	107	26	64	128	18	47	42	P = 0.05
8	Southern Turkey [26]	176	131	6	81	89	14	66	51	P = 0.01
9	Caucasian [27]	540	349	120	262	158	75	173	101	p > 0.05
10	China [28]	114	157	50	46	18	62	63	32	p = 0.42
11	India [29]	203	212	61	88	54	59	80	73	p = 0.21

ISSN: 1471-2261