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Table 3 Increased risk (95% Confidence Intervals) for moderate/high 10-Year Cardiovascular Disease according to Italian CUORE Risk Score (CRS), estimate by logistic regression models

From: Homocysteine and education but not lipoprotein (a) predict estimated 10-year risk of cardiovascular disease in blood donors: a community based cross-sectional study

 

CRS 10-Year CVD risk

  

CRS 10-Year CVD risk

  

OR (95% CI)

Homocysteine (ÎĽmol/l)

P

R2

OR (95% CI)

Low educational

P

R2

Model 1

1.08 (1.049–1.121)

< 0.001

0.025

1.55 (1.124–2.148)

0.008

0.006

Model 2

1.08 (1.049–1.123)

< 0.001

0.041

1.52 (1.095–2.110)

0.012

0.014

Model 3

1.08 (1.050–1.124)

< 0.001

0.053

1.49 (1.067–2.082)

0.019

0.028

Model 4

1.09 (1.047–1.126)

< 0.001

0.112

1.59 (1.114–2.296)

0.011

0.098

Model 5

1.09 (1.048–1.134)

< 0.001

0.179

1.69 (1.164–2.472)

0.006

0.153

Model 6

1.09 (1.046–1.138)

< 0.001

0.263

1.61 (1.070–2.428)

0.022

0.237

Model 7

–

–

–

1.71 (1.092–2.703)

0.019

0.263

  1. Model 1 = Unadjusted; Model 2 = Model 1 and further adjusted for socio-demographic variable (marital status and educational attainment); Model 3 = Additionally adjusted for lifestyle (cigarettes/day and physical activity/week); Model 4 = Additionally adjusted for anthropometric variable (BMI and waist circumference); Model 5 = Additionally adjusted for diastolic blood pressure; Model 6 = Additionally adjusted for metabolic risk factors (LDL-Cholesterol, triglycerides and fasting glucose). Model 7 = Additionally adjusted for homocysteine