Table 2 Clinical, biochemical and socio-demographic characteristics of blood donors stratified according to homocysteine and lipoprotein (a) levels
Overall | Hcy < 15 N (%) = 920 (88.6) | Hcy ≥15 N (%) = 118 (11.4) | p-value | Lp (a) < 30 N (%) = 597 (77.6) | Lp (a) ≥30 N (%) = 172 (22.4) | p-value | |
|---|---|---|---|---|---|---|---|
Age, n (%) [N = 1,445] | 0.253 | 0.560 | |||||
18–29 | 120 (8.3) | 67 (7.3) | 3 (2.5) | 44 (7.4) | 7 (4.1) | ||
30–40 | 299 (20.6) | 182 (19.8) | 23 (19.5) | 96 (16.1) | 26 (15.1) | ||
41–50 | 638 (44.1) | 389 (42.4) | 51 (42.5) | 256 (42.9) | 75 (43.6) | ||
51–60 | 322 (22.3) | 237 (25.7) | 33 (27.9) | 168 (28.1) | 55 (32) | ||
> 60 | 68 (4.6) | 44 (4.8) | 9 (7.6) | 33 (5.5) | 9 (5.2) | ||
Gender, n(%) | < 0.001 | 0.011 | |||||
Male | 886 (61.2) | 542 (59.1) | 103 (87.3) | 396 (66.3) | 96 (55.8) | ||
Female | 561 (38.8) | 375 (40.9) | 15 (12.7) | 201 (33.7) | 76 (44.2) | ||
Marital Status, n (%) [N = 1,420] | 0.631 | 0.840 | |||||
Unmarried | 331 (23.3) | 195 (21.4) | 20 (17.1) | 117 (19.8) | 34 (20) | ||
Married | 972 (68.4) | 633 (69.6) | 87 (74.4) | 420 (71.1) | 120 (70.6) | ||
Divorced/separated | 105 (7.4) | 71 (7.8) | 8 (6.8) | 46 (7.8) | 15 (8.8) | ||
Widow/er | 12 (0.8) | 10 (1.1) | 2 (1.7) | 8 (1.3) | 1 (0.6) | ||
Educational attainment, n (%) [N = 1,286] | 0.820 | 0.859 | |||||
HEA | 1,016 (79) | 715 (79.4) | 91 (78.4) | 453 (77.4) | 129 (76.8) | ||
LEA | 270 (21) | 186 (20.6) | 25 (21.5) | 132 (22.6) | 39 (23.2) | ||
Smokers, n (%) [N = 1,436] | 0.576 | 0.701 | |||||
Yes | 299 (20.8) | 189 (20.7) | 27 (22.9) | 123 (20.6) | 33 (19.3) | ||
No | 1,137 (79.2) | 726 (79.3) | 91 (77.1) | 473 (79.4) | 138 (80.7) | ||
Cigarettes/day, mean (SD) | 2 (4.9) | 1.9 (4.9) | 2.4 (5.4) | 0.375 | 2 (4.8) | 2 (5.7) | 0.843 |
Regular physical activity, n (%) [N = 1,437] | 0.869 | ||||||
Yes | 823 (57.3) | 520 (56.8) | 68 (57.6) | 335 (56.2) | 96 (56.1) | 0.987 | |
No | 614 (42.7) | 395 (43.2) | 50 (42.4) | 261 (43.8) | 75 (43.9) | ||
Physical activity/week, mean (SD) | 1.6 (1.7) | 1.5 (1.6) | 1.5 (1.8) | 0.877 | 1.4 (1.5) | 1.6 (1.9) | 0.154 |
Anthropometric indices, mean (SD) | |||||||
BMI (Kg/m2), [N = 1,435] | 25.8 (3.9) | 25.7 (3.7) | 26.8 (4.3) | 0.004 | 26 (3.7) | 25.8 (3.8) | 0.569 |
Waist circumference (cm), [N = 1,242] | 91.3 (11.8) | 90.8 (11.8) | 94.1 (12.2) | 0.005 | 91.5 (12.3) | 90.7 (11.6) | 0.499 |
CVD RF measurements, mean (SD) | |||||||
Fasting Glucose (mmol/l), [N = 1,415] | 5.40 (12.5) | 5.41 (11.5) | 5.58 (13.6) | 0.010 | 5.46 (10.6) | 5.45 (17.3) | 0.870 |
Systolic Blood Pressure (mm/Hg), [1,396] | 120.5 (7.2) | 120.2 (6.7) | 122.2 (7.8) | 0.003 | 120.9 (7.8) | 119.8 (5.9) | 0.083 |
Diastolic Blood Pressure (mm/Hg) | 75.6 (6.2) | 75.4 (6.1) | 76.4 (6.9) | 0.100 | 75.8 (6.5) | 75.3 (6.0) | 0.398 |
Total Cholesterol (mmol/l), [1,424] | 5.11 (35) | 5.11 (35.2) | 5.12 (33.6) | 0.942 | 5.08 (33.1) | 5.33 (35.8) | 0.002 |
Triglycerides (mmol/l) | 1.16 (75) | 1.13 (67.9) | 1.23 (62.7) | 0.193 | 1.17 (73) | 1.09 (57.4) | 0.251 |
HDL Cholesterol (mmol/l), [N = 1,360] | 1.42 (13.3) | 1.40 (12.9) | 1.32 (12.3) | 0.022 | 1.38 (12.6) | 1.43 (12.3) | 0.087 |
LDL Cholesterol (mmol/l), [N = 1,344] | 3.58 (36.2) | 3.63 (36.6) | 3.70 (35.7) | 0.468 | 3.61 (37.3) | 3.87 (36.3) | 0.002 |
Quality of life, mean (SD), [1,189] | |||||||
SF-12 PCS | 52.6 (5.6) | 52.5 (5.7) | 52 (5.9) | 0.377 | 52.6 (5.3) | 52 (6.2) | 0.181 |
SF-12 MCS | 48.6 (9.4) | 48.4 (9.3) | 49.4 (9.3) | 0.320 | 48.6 (8.9) | 47.7 (10.7) | 0.266 |