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Table 2 Clinical characteristics of patients with and without MACE

From: Prognostic implications of statin intolerance in stable coronary artery disease patients with different levels of high-sensitive troponin

 

With MACE

N = 148

Without MACE

N = 804

P-value

Age, years

72 ± 9

66 ± 11

< 0.01

Age ≥ 65 years, n (%)

120 (81)

438 (54)

< 0.01

Male, n (%)

98 (66)

598 (74)

0.040

Current smoker, n (%)

29 (20)

131 (16)

0.32

Hypertension, n(%)

129 (87)

587 (73)

< 0.01

Diabetes mellitus, n (%)

86 (51)

260 (32)

< 0.01

Baseline lipid profile*

Total cholesterol, mmol/L

4.2 ± 1.1

4.0 ± 1.0

0.17

Triglyceride, mmol/L

1.5 ± 1.0

1.5 ± 1.0

0.71

HDL-C, mmol/L

1.2 ± 0.5

1.2 ± 0.3

0.51

LDL-C, mmol/L

2.2 ± 1.0

2.1 ± 0.8

0.13

LDL-C < 1.8 mmol/L, n (%)

56 (37.8)

303 (37.7)

0.97

Non-HDL-C, mmol/L

3.0 ± 1.1

2.8 ± 1.0

0.10

Follow-up lipid profile

Total cholesterol, mmol/L

3.7 ± 0.8

3.8 ± 0.8

0.17

Triglyceride, mmol/L

1.4 ± 0.9

1.4 ± 0.9

0.86

HDL-C, mmol/L

1.2 ± 0.4

1.2 ± 0.4

0.16

LDL-C, mmol/L

1.9 ± 0.7

1.9 ± 0.6

0.65

LDL-C < 1.8 mmol/L, n (%)

69 (46.6)

343 (42.7)

0.37

Non-HDL-C, mmol/L

2.5 ± 0.7

2.5 ± 0.7

0.45

Statin intolerance, n (%)

41 (27.7)

97 (12.1)

< 0.01

Ln hs-cTnI, pg/ml

3.1 ± 1.6

2.0 ± 1.2

< 0.01

  1. *Baseline lipid profile was taken after the diagnosis of CAD was confirmed by coronary angiography
  2. Abbreviations: HDL-C high density lipoprotein cholesterol, hs-cTnl high-sensitive cardiac troponin I, Ln natural logarithm, LDL-C low density lipoprotein cholesterol, MACE major adverse cardiovascular events