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Table 1 Baseline patient and disease characteristics

From: Balloon-expandable transcatheter aortic valve implantation with or without pre-dilation – results of a meta-analysis of 3 multicenter registries

 

N

TAVI with BAV

N = 339

TAVI without BAV

N = 355

P-value

Patient characteristics

 Age (years)

694

82 (79–86)

81 (78–86)

0.057

 Female (%)

694

49.9

45.4

0.254

 Height (cm)

694

166 (160–172)

168 (160–175)

0.052

 Weight (kg)

694

72 (63–82)

75 (63–87)

0.027

 Body surface area (cm2)a

694

1.81 (1.68–1.94)

1.84 (1.68–2.01)

0.032

 BMI (kg/m2)

692

26 (23–29)

26 (24–30)

0.207

 Hypertension (%)

678

85.2

88.4

0.255

 Diabetes (%)

676

31.0

32.9

0.621

 Stroke, TIA (%)

678

13.5

16

0.387

 Peripheral artery disease (%)

679

43.4

23.9

< 0.001

 Pulmonary hypertension (%)

527

33.0

38.6

0.202

 Creatinine > 2 mg/dL (%)

694

5.9

6.2

0.875

 Dialysis (%)

361

6.4

2.7

0.108

 Coronary artery disease (%)

694

61.9

64.8

0.478

 Prior myocardial infarction (%)

557

29.8

24.4

0.182

 Prior CV intervention (%)

694

36.3

44.8

0.025

 Prior pacemaker / ICD implant (%)

501

17.6

12.7

0.152

 EuroSCORE II

588

4 (2–8)

5 (3–10)

0.005

 STS Risk Score

616

5.3 (3.2–10.0)

4.6 (3.0–8.0)

0.002

Disease characteristics

 Echo AV peak PG (mmHg)

533

70 (57–82)

69 (55–81)

0.275

 Echo AV mean PG (mmHg)

649

43 (35–54)

41 (33–50)

0.111

 Echo Vmax (m/s)

435

4.0 (3.7–4.4)

4.1 (3.6–4.5)

0.965

 Echo ejection fraction (%)

653

55 (47–60)

55 (45–60)

0.324

 Effective orifice area

534

0.70 (0.57–0.80)

0.70 (0.60–0.80)

0.043

 Indexed effective orifice areab

533

0.38 (0.31–0.46)

0.39 (0.32–0.46)

0.348

 NYHA Class III or IV

685

79.8

75.9

0.232

 CCS grading of angina pectoris Class III or IV

645

16.8

17.0

1.000

 Dizziness or syncope

694

30.1

30.1

1.000

  1. Values are median (interquartile range) unless indicated otherwise
  2. AV Aortic valve, BAV Balloon aortic valvuloplasty, BMI Body mass index, CCS Canadian cardiovascular society, CV Cardiovascular, EuroSCORE European system for cardiac operative risk evaluation, ICD Implantable cardioverter defibrillator, NYHA New York Heart Association, PG Pressure gradient, STS Society of thoracic surgeons, TAVI Transcatheter aortic valve implantation, TIA Transient ischemic attack, Vmax Maximum velocity
  3. aBSA [cm x kg] = 0.007184 x height [cm]0.725 x weight [kg]0.425 (DuBois, 1916)
  4. biEOA Effective orifice area/body surface area