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Table 1 Clinic characteristics of type 2 diabetic patients with or without PAD

From: Vitamin D deficiency is associated with risk of developing peripheral arterial disease in type 2 diabetic patients

 

NPAD (N = 940)

PAD (N = 78)

P

Age, years

57.82 ± 11.12

67.88 ± 9.77

0.000

Male, n(%)

526 (56.0%)

38 (48.7%)

0.216

BMI, kg/m2

25.58 ± 3.36

26.08 ± 3.62

0.204

Smoking status, n(%)

 never

589 (62.7%)

45 (55.7%)

 

 former

105 (11.2%)

15 (19.2%)

0.104

 current

246 (26.2%)

18 (23.1%)

 

Duration of diabetes

 ≥10 years

565 (60.1%)

57 (73.1%)

0.024

 <10 years

375 (39.9%)

21 (26.9%)

 

Hypertension, n(%)

525 (55.9%)

62 (79.5%)

0.000

Hyperlipidemia, n (%)

505 (53.7%)

46 (59.0%)

0.371

CHD, n (%)

201 (21.4%)

37 (47.4%)

0.000

Cerebral infarction, n (%)

119 (12.7%)

20 (25.6%)

0.001

Diabetic retinopathy, n (%)

 NDR

665 (70.7%)

39 (50.0%)

 

 NPDR

171 (18.2%)

24 (30.8%)

0.001

 PDR

104 (11.1%)

15 (19.2%)

 

GFR, ml/min

92.22 ± 19.92

75.33 ± 19.90

0.000

HbA1c, %

8.77 ± 1.82

9.12 ± 1.71

0.108

Serum creatinine, umol/L

65.34 ± 15.17

72.77 ± 17.97

0.001

Serum uric acid, mmol/L

329.92 ± 79.93

340.85 ± 82.75

0.253

TC, mmol/L

4.47 ± 0.99

4.55 ± 1.17

0.488

LDL, mmol/L

2.68 ± 0.84

2.74 ± 0.97

0.598

HDL, mmol/L

1.20 ± 0.31

1.02 ± 0.27

0.712

TG, mmol/L

1.85 ± 1.57

1.96 ± 1.23

0.537

Serum 25(OH)D, ng/ml

14.81 ± 8.43

11.55 ± 5.65

0.000

Serum calcium, mmol/L

2.25 ± 0.09

2.26 ± 0.10

0.412

Serum phosphate, mmol/L

1.26 ± 0.17

1.24 ± 0.16

0.314

ALP, mmol/L

73.42 ± 22.2

73.35 ± 23.33

0.978

  1. NPAD no peripheral arterial disease, PAD peripheral arterial disease, BMI body mass index, CHD coronary heart disease, NDR non-diabetic retinopathy, NPDR non-proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy, GFR glomerular filtration rate, HbA1c glycated hemoglobin, TC total cholesterol, LDL low density lipoprotein, HDL high density lipoprotein, TG triglycerides, 25(OH)D 25-hydroxyvitamin D, ALP alkaline phosphatase