Fig. 4

CCK-8 assay and AV/PI assay in lnc-NEAT1 shRNA transfected I/R injury H9c2 cells. Compared to normal&sh-NC group, cell proliferation was reduced in OGD/R&sh-NC group at 48 h and 72 h but increased in OGD/R&sh-NEAT1 group at 48 h and 72 h compared to OGD/R&sh-NC group (a). Cell apoptosis rate was raised in OGD/R&sh-NC group compared to normal&sh-NC group at 72 h but decreased in OGC/R&sh-NEAT1 group compared to OGD/R&sh-NC group (b-c). Lnc-NEAT1, long non-coding RNA nuclear enriched abundant transcript 1. OGD/R, oxygen and glucose deprivation followed by reperfusion. p < 0.05 was considered significant. ***p < 0.001, OGD/R&sh-NC group vs. Normal&sh-NC group; **p < 0.01, OGD/R&sh-NC group vs. Normal&sh-NC group; ##p < 0.01, OGD/R&sh-NEAT1 group vs. OGD/R&sh-NC group