Skip to main content

Table 3 Other Sensitivity Analyses for Propensity Score Matched Patients

From: Effectiveness and safety of direct oral anticoagulants compared to warfarin in treatment naïve non-valvular atrial fibrillation patients in the US Department of defense population

 

Dabigatran vs Warfarin

Rivaroxaban vs Warfarin

Apixaban vs Warfarin

Censoring at 6 Months, HR (95% CI)

 Sample Size

N = 3691 vs N = 3691

N = 8226 vs N = 8226

N = 7607 vs N = 7607

 Stroke/SE

0.68 (0.37–1.23)

0.90 (0.63–1.29)

0.51 (0.33–0.79)

 Major bleeding

1.10 (0.75–1.61)

1.12 (0.91–1.39)

0.59 (0.45–0.77)

Intent-to-Treat, HR (95% CI)

 Sample Size

N = 3691 vs N = 3691

N = 8226 vs N = 8226

N = 7607 vs N = 7607

 Stroke/SE

0.76 (0.57–1.03)

1.04 (0.86–1.26)

0.63 (0.49–0.81)

 Major bleeding

0.97 (0.80–1.19)

1.01 (0.89–1.15)

0.75 (0.64–0.88)

Excluding Patients with Catheter Ablation or Cardioversion, HR (95% CI)

 Sample Size

N = 3298 vs N = 3298

N = 7698 vs N = 7698

N = 7034 vs N = 7034

 Stroke/SE

0.68 (0.43–1.07)

0.83 (0.64–1.09)

0.55 (0.39–0.77)

 Major bleeding

1.05 (0.79–1.40)

1.07 (0.91–1.27)

0.65 (0.53–0.80)

  1. CI Confidence interval, HR Hazard ratio, SE Systemic embolism