CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population

Table 5 CD36 rs1761667-related studies

Ethnicity of the population	Sample sizes		Clinical condition	minor allele	MAF	P-value	association results	P- valuae	Ref.
Ethnicity of the population	case	control	Clinical condition	minor allele	MAF	P-value	association results	P- valuae	Ref.
Mexican	309	132	overweight and obese	G	0.4	0.06	high serum cholesterol levels were associated with the AA genotype	0.005	[24]
Indian	250	150	T2DM	A	0.36	0.24	A allele is significantly associated with T2DM	< 0.005	[22]
Egyptian	100	100	MetS	G	0.25	0.00	Subjects with AG and GG genotypes had significantly higher systolic blood pressure, wider waist circumstance, and higher degree of dyslipidemia	< 0.001	[23]
Algerian	57	59	Obese and lean children	A	0.47	0.036	A allele was higher in obese subjects	0.03	[25]
Chongqing Han population of China	112	129	CHD	A	0.31	0.480	Significantly higher frequency of the AG genotype in the CHD group compared to the control group. The plasma levels of ox-LDL in CHD patients with AG genotype were significantly higher	0.011 0.010	[13]
Chinese Han	374	1013	atherothrombotic stroke	A	0.35	0.113	A allele were associated with atherothrombotic stroke in Chinese Han	0.020	[21]
Egyptian	71	76	CAD	A	0.46	0.680	The AG genotype involved in CAD pathogenesis as well as increased BMI, T2DM and MetS	0.001	[12]
Chinese Han	215	252	carotid atherosclerotic	A	0.33	0.135	GA genotypes increase the susceptibility of females to carotid atherosclerosis	0.041	[16]

MAF Minor allele frequency, CAD Coronary artery disease, CHD Coronary artery heart disease, T2DM Type 2 diabetes mellitus, MetS Metabolic syndrome, HDL High-density lipoprotein, LDL Low-density lipoprotein, TG Triglycerides, BMI Body mass index, ox-LDL Oxidized LDL

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