CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population

Momeni-Moghaddam, Mohammad Amin; Asadikaram, Gholamreza; Akbari, Hamed; Abolhassani, Moslem; Masoumi, Mohammad; Nadimy, Zahra; Khaksari, Mohammad

doi:10.1186/s12872-019-1111-6

Table 3 Patient characteristics and distribution of CD36 rs1761667 genotypes in H-Tens, CAD + H-Tens, CAD and Ctrl subjects

From: CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population

		Age (years)	BMI (kg/m²)	FBS (mg/dl)	TG (mg/dl)	TC (mg/dl)	HDL-c (mg/dl)	LDL-c (mg/dl)	Na (mmol/l)	K (mmol/l)	Cr (mg/dl)	Urea (mg/dl)	SBP (mmHg)	DBP (mmHg)
H-Tens	GG	55.50 ± 6.95	27.35 ± 9.43	97.17 ± 6.55	90.33 ± 22.59	144.17 ± 24.28	43.67 ± 5.57	82.43 ± 26.70	140.33 ± 4.32	4.43 ± 0.33	0.89 ± 0.16	34.50 ± 5.28	116.67 ± 10.32	71.67 ± 7.52
	GA	54.90 ± 9.86	27.11 ± 5.05	94.90 ± 11.42	118.68 ± 63.43	140.55 ± 32.75	37.95 ± 9.65	75.89 ± 28.86	139.33 ± 3.11	4.34 ± 0.42	0.99 ± 0.17	35.88 ± 10.72	124.43 ± 15.31	74.78 ± 9.01
	AA	52.50 ± 4.68	26.09 ± 4.20	86.83 ± 22.40	126.83 ± 42.75	159.33 ± 40.80	34.50 ± 12.39	103.63 ± 41.48	140.67 ± 3.14	4.30 ± 0.70	0.95 ± 0.46	33.83 ± 12.84	120.00 ± 12.64	75.83 ± 13.57
	P-value	0.816	0.906	0.825	0.323	0.433	0.252	0.119	0.545	0.869	0.483	0.682	0.519	0.712
	GG	57.47 ± 12.84	25.37 ± 3.39	93.76 ± 16.23	145.06 ± 80.98	145.18 ± 35.81	34.18 ± 6.53	81.98 ± 27.67	139.24 ± 3.23	4.31 ± 0.32	1.08 ± 0.21	35.59 ± 10.13	122.06 ± 13.17	69.88 ± 17.39
CAD + H-Tens	GA	56.43 ± 10.21	24.75 ± 4.92	96.43 ± 20.60	94.24 ± 32.39^#	131.11 ± 32.67	37.73 ± 9.96	74.69 ± 27.83	139.49 ± 3.09	4.16 ± 0.36	1.06 ± 0.20	35.03 ± 8.84	120.68 ± 13.75	73.92 ± 8.89
	AA	50.00 ± 12.72	24.19 ± 6.49	87.50 ± 6.36	91.50 ± 24.74	159 ± 43.84	50.50 ± 17.67	90.20 ± 31.10	135.50 ± 0.70	3.90 ± 0.56	0.98 ± 0.17	40.50 ± 6.36	125.00 ± 7.07	75.00 ± 7.07
	P-value	0.661	0.904	0.337	0.018	0.235	0.055	0.619	0.218	0.206	0.782	0.609	0.670	0.858
	GG	56.18 ± 12.27	24.77 ± 4.93	98.45 ± 22.10	107.45 ± 43.05	139.73 ± 38.73	38.18 ± 6.12	80.05 ± 35.32	138.00 ± 3.16	4.00 ± 0.32	0.99 ± 0.11	35.27 ± 8.27	113.89 ± 12.69	70.56 ± 8.82
CAD	GA	56.69 ± 9.26	24.50 ± 4.36	92.78 ± 12.43	112.22 ± 61.85	144.82 ± 40.45	38.18 ± 11.12	84.41 ± 34.95	140.18 ± 2.88^#	4.43 ± 42^#	1.11 ± 0.20	35.60 ± 10.82	114.77 ± 11.61	70.23 ± 7.99
	AA	54.13 ± 8.09	23.30 ± 3.59	99.25 ± 18.21	102.63 ± 56.64	148.00 ± 40.63	42.25 ± 12.06	86.17 ± 30.52	138.38 ± 2.32	4.22 ± 0.37	1.14 ± 0.15	37.88 ± 10.64	120.00 ± 10.69	68.75 ± 8.34
	P-value	0.783	0.726	0.350	0.718	0.559	0.590	0.358	0.047	0.007	0.099	0.667	0.474	0.868
	GG	52.65 ± 9.69	25.59 ± 5.42	95.73 ± 12.02	112.19 ± 39.83	151.42 ± 48.91	41.00 ± 12.38	87.98 ± 44.25	139.12 ± 2.79	4.28 ± 0.37	1.02 ± 0.18	32.38 ± 9.58	120.58 ± 11.52	75.96 ± 8.12
Ctrl	GA	55.93 ± 10.59	25.02 ± 4.97	96.73 ± 16.44	101.13 ± 36.03	142.97 ± 40.78	41.20 ± 7.35	76.50 ± 37.52	139.39 ± 3.20	4.34 ± 0.48	1.03 ± 0.22	33.73 ± 10.64	124.83 ± 16.68	76.37 ± 8.52
	AA	50.71 ± 12.07	23.46 ± 5.02	89.86 ± 15.61	121.14 ± 38.36	166.29 ± 57.22	45.86 ± 13.33	96.20 ± 47.05	138.57 ± 3.15	4.22 ± 0.53	1.14 ± 0.38	48.00 ± 0.22	113.89 ± 10.54	71.67 ± 7.07
	P-value	0.230	1.308	0.802	1.415	1.228	0.269	1.455	0.683	0.256	0.828	0.069	0.096	0.269

H-Tens Hypertension, CAD + H-Tens Coronary Artery Disease and Hypertension, CAD Coronary Artery Disease, Ctrl Control, BMI Body mass index, FBS Fasting blood sugar, TC Total cholesterol, TG Triglycerides, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, Na Sodium, K potassium, Cr Creatinine, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure
Values are presented as mean ± SD. ^# Significant differences GG genotype (P < 0.05)

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