Oestradiol: any role in cardiovascular risk factors in female centenarians of Hainan?

Table 3 Multiple Logistic Regression between E2 and CVD Risk Factors

Variable		1st quartile	2nd quartile	3rd quartile	4th quartile
Variable		OR (95%CI)	OR (95%CI)	OR (95%CI)	OR (95%CI)
Hypertension
Stage 1	Unadjusted	1.18 (0.51–2.72)	0.95 (0.42–2.13)	0.66 (0.31–1.42)	1.00
Stage 1	Adjusted	1.13 (0.48–2.64)	0.85 (0.37–1.96)	0.62 (0.28–1.38)	1.00
Stage 2	Unadjusted	1.38 (0.45–4.20)	1.36 (0.47–3.99)	1.34 (0.49–3.72)	1.00
Stage 2	Adjusted	1.31 (0.42–4.08)	1.23 (0.41–3.69)	1.21 (0.43–3.46)	1.00
High TC ^a	Unadjusted	–	5.60 (1.83–17.10)^**	2.39 (1.03–5.56)^*	1.00
High TC ^a	Adjusted	–	5.75 (1.85–17.83)^**	2.34 (0.99–5.50)	1.00
High TG	Unadjusted	1.43 (0.44–4.66)	3.68 (0.75–18.17)	1.82 (0.52–6.43)	1.00
High TG	Adjusted	1.51 (0.43–5.31)	3.88 (0.74–20.48)	1.71 (0.45–6.55)	1.00
Low HDL	Unadjusted	1.88 (0.61–5.81)	3.08 (1.07–8.91)^**	2.80 (0.96–8.16)	1.00
Low HDL	Adjusted	2.17 (0.68–6.96)	3.27 (1.10–9.71)^**	3.17 (1.05–9.51)^**	1.00
High LDL	Unadjusted	9.29 (2.08–41.53)^**	3.61 (1.27–10.25)^**	1.94 (0.82–4.62)	1.00
High LDL	Adjusted	10.22 (2.22–46.98)^**	3.63 (1.25–10.51)^**	1.83 (0.76–4.43)	1.00

The prevalence of hypertension, high level of TC, TG, LDL-C and low level of HDL-C was demonstrated according to quartiles of estradiol
The cut-off points for dyslipidemia were plasma TC ≥ 240 mg/dl and/or use of medications to lower blood cholesterol for high TC, TG ≥ 200 mg/dl for high TG, HDL-C<40 mg/dl for low HDL-C, and LDL-C ≥ 160 mg/dl and/or use of medications to lower blood cholesterol for high LDL-C
According to the level of E2, quartiles are used for grouping (1st quartile:≥19.4,2nd quartile:19.5–40.3, 3rd quartile:40.4–62.9 4th quartile:≥63.0) The odds ratios were presented as unadjusted and further adjusted for age, BMI, WC, WHR and the number of children
^a No centenarian with concentration of TC higher than 240 mg/dl in the first quartile thus the data was unavailable in this column
*P < 0.05, **P < 0.01

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