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Table 4 Adjusted hazard ratios for predictors of primary outcomes in total study cohort (Group 1)

From: Usage of PCI and long-term cardiovascular risk in post-myocardial infarction patients: a nationwide registry cohort study from Finland

 

Myocardial infarction

Ischemic stroke

Cardiovascular mortality

Overall mortality

HR

P

HR

P

HR

P

HR

P

Age (vs < 50)

 50–64

1.018

0.841

2.058

0.003

2.013

0.078

2.020

< 0.001

 65–69

1.309

0.004

2.690

< 0.001

2.162

0.063

2.250

< 0.001

 70–74

1.308

0.003

3.229

< 0.001

3.572

0.001

2.962

< 0.001

 75–79

1.676

< 0.001

3.736

< 0.001

4.804

< 0.001

3.736

< 0.001

 80–84

2.038

< 0.001

4.476

< 0.001

5.160

< 0.001

4.251

< 0.001

 85 and over

2.745

< 0.001

4.953

< 0.001

8.894

< 0.001

6.476

< 0.001

Female sex (vs male)

0.887

< 0.001

0.905

0.085

0.789

0.002

0.782

< 0.001

STEMI as index event (vs NSTEMI)

0.881

< 0.001

1.118

0.074

0.842

0.066

0.843

< 0.001

PCI or CABG related to index MI

0.650

< 0.001

0.673

< 0.001

0.502

< 0.001

0.493

< 0.001

Atrial fibrillation

1.014

0.725

1.408

< 0.001

1.057

0.528

1.143

0.003

Diabetes mellitus

1.371

< 0.001

1.257

< 0.001

1.494

< 0.001

1.361

< 0.001

Chronic renal failure

1.788

< 0.001

1.310

0.062

1.265

0.193

1.762

< 0.001

Dementia/Alzheimer’s disease

0.979

0.726

0.969

0.768

2.029

< 0.001

2.541

< 0.001

Ischemic stroke or TIA

1.114

0.017

4.169

< 0.001

1.601

< 0.001

1.332

< 0.001

Major bleedings

1.170

0.002

1.144

0.126

1.243

0.052

1.352

< 0.001

Hypertension

0.910

0.332

1.319

0.245

0.659

0.052

0.582

< 0.001

Hyperlipidemia

1.016

0.701

0.974

0.745

0.721

< 0.001

0.616

< 0.001

Congestive heart failure

1.385

< 0.001

1.219

0.002

2.000

< 0.001

2.018

< 0.001

Severe liver disease

1.232

0.353

1.870

0.061

0.721

0.645

1.283

0.381

COPD

1.156

0.032

0.950

0.706

1.842

< 0.001

1.915

< 0.001

Malignancy

1.160

0.003

1.272

0.006

0.975

0.841

1.668

< 0.001

  1. Abbreviations: CABG coronary artery bypass grafting, MI myocardial infarction, NSTEMI non-ST-elevation myocardial infarction, PCI percutaneous coronary intervention, STEMI ST-elevation myocardial infarction, TIA transient ischemic attack
  2. The multivariate model simultaneously included all the variables listed in this table and in addition ongoing selective serotonin reuptake inhibitor use, and ongoing oral antiplatelet use
  3. The full statistical model for Group 1 and Group 2 for all outcomes is presented in Additional file 1: Table S1