Table 2 Change in metabolic parameters after parathyroidectomy
Variables | Normocalcemic PHPT (n = 30) | Hypercalcemic PHPT (n = 50) | ||||
|---|---|---|---|---|---|---|
Pre-PTX | Post-PTX | P | Pre-PTX | Post-PTX | P | |
BMI (kg/m2) | 29.97 ± 3.73 | 29.98 ± 3.65 | 0.372 | 31.09 ± 5.17 | 29.47 ± 5.61 | 0.532 |
Waist-hip-ratio | 0.89 ± 0.05 | 0.88 ± 0.05 | 0.177 | 0.89 ± 0.06 | 0.88 ± 0.68 | 0.363 |
Diastolic BP (mmHg) | 82.3 ± 5.8 | 79.36 ± 7.74 | 0.040 | 83.2 ± 7.6 | 77.01 ± 7.38 | 0.008 |
Systolic BP (mmHg) | 136.6 ± 16.5 | 126.57 ± 16.57 | 0.003 | 138.9 ± 16.4 | 119.73 ± 12.95 | 0.001 |
iPTH (pg/ml) | 145.8 ± 40.1 | 71.52 ± 21.50 | < 0.001 | 188.5 ± 93.3 | 48.60 ± 18.97 | 0.001 |
Albumin-corrected calcium (mg/dl) | 9.85 ± 0.30 | 8.91 ± 0.38 | < 0.001 | 11.25 ± 0.69 | 9.02 ± 0.32 | 0.001 |
Phosphorus (mg/dl) | 2.98 ± 0.48 | 3.20 ± 0.41 | 0.002 | 2.57 ± 0.41 | 3.21 ± 0.47 | 0.001 |
ALP (IU/L) | 103.51 ± 40.82 | 86.89 ± 25.10 | < 0.001 | 107.00 ± 44.27 | 84.33 ± 2.54 | 0.001 |
Glucose (mg/dl) | 93.11 ± 12.19 | 86.36 ± 5.97 | 0.120 | 95.00 ± 14.80 | 82.26 ± 6.70 | 0.009 |
İnsulin (μIU/ml) | 13.26 ± 6.19 | 11.47 ± 3.08 | 0.006 | 13.33 ± 5.24 | 10.83 ± 4.62 | 0.125 |
HOMA-IR | 3.06 ± 1.47 | 2.57 ± 0.81 | 0.024 | 3.13 ± 1.25 | 2.25 ± 0.92 | 0.031 |
Total cholesterol (mg/dl) | 210.09 ± 39.46 | 204.06 ± 41.92 | 0.002 | 204.80 ± 37.98 | 185.97 ± 28.62 | 0.017 |
LDL-C (mg/dl) | 129.20 ± 33.11 | 127.73 ± 36.71 | 0.004 | 123.54 ± 30.33 | 109.41 ± 16.65 | 0.094 |
HDL-C (mg/dl) | 49.17 ± 10.56 | 49.94 ± 7.96 | 0.046 | 49.34 ± 11.29 | 49.01 ± 11.06 | 0.138 |
TG (mg/dl) | 158.60 ± 61.78 | 137.84 ± 61.55 | 0.019 | 159.57 ± 67.34 | 132.93 ± 53.95 | 0.172 |
Creatinine clerance (ml/min/1.73 m2) | 112.89 ± 27.26 | 123.36 ± 31.44 | 0.777 | 107.15 ± 28.37 | 121.75 ± 39.10 | 0.198 |
Cardiovascular risk score | 11.98 ± 10.11 | 7.37 ± 4.48 | 0.001 | 14.62 ± 11.06 | 8.05 ± 7.72 | 0.005 |